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Catalog Number:
01346
CAS Number:
15387-45-8
Boc-L-glutamine 4-nitrophenyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Gln-ONp
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Product Information

Boc-L-glutamine 4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This protected form of L-glutamine features a 4-nitrophenyl ester moiety, which enhances its reactivity and solubility, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry. Its unique structure allows for selective activation in various coupling reactions, facilitating the formation of peptide bonds with high efficiency.

This compound is particularly beneficial in the development of peptide-based therapeutics and in the study of protein interactions, where precise modifications are crucial. Its stability under standard laboratory conditions ensures reliable performance in synthetic protocols. Additionally, Boc-L-glutamine 4-nitrophenyl ester can serve as a valuable building block in the synthesis of more complex molecules, offering researchers a robust tool for advancing their projects. With its combination of reactivity and stability, this compound stands out as a preferred choice for professionals seeking to enhance their synthetic capabilities.

Synonyms
Boc-L-Gln-ONp
CAS Number
15387-45-8
Purity
≥ 98% (HPLC)
Molecular Formula
C16H21N3O7
Molecular Weight
367.4
MDL Number
MFCD00065572
PubChem ID
85834
Melting Point
142-148 °C
Appearance
White powder
Optical Rotation
[α]D20 = -33 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Gln-ONp
CAS Number
15387-45-8
Purity
≥ 98% (HPLC)
Molecular Formula
C16H21N3O7
Molecular Weight
367.4
MDL Number
MFCD00065572
PubChem ID
85834
Melting Point
142-148 °C
Appearance
White powder
Optical Rotation
[α]D20 = -33 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-glutamine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the efficient coupling of amino acids.
  • Drug Development: It is employed in the development of pharmaceutical compounds, especially those targeting glutamine pathways, which are crucial in cancer metabolism and other diseases.
  • Bioconjugation: The ester functionality enables bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, enhancing drug delivery systems.
  • Analytical Chemistry: Used as a standard in chromatographic techniques, it helps in the quantification and analysis of glutamine derivatives in various samples.
  • Research in Neurobiology: Its role in studying neurotransmitter pathways makes it significant for research into neurological disorders, providing insights into glutamate and its analogs.

Citations