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Catalog Number:
01333
CAS Number:
50913-12-7
Nα-Boc-Nω-nitro-D-arginine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-D-Arg(NO2)-OH
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Product Information

Na-Boc-Nw-nitro-D-arginine is a specialized amino acid derivative that plays a crucial role in biochemical research and pharmaceutical applications. This compound is recognized for its unique nitro group, which enhances its reactivity and makes it a valuable building block in the synthesis of various bioactive molecules. Its protective Boc (tert-butyloxycarbonyl) group allows for selective reactions, making it an ideal candidate for peptide synthesis and modification. Researchers utilize Na-Boc-Nw-nitro-D-arginine in the development of nitric oxide donors and in studies related to cardiovascular health, where modulation of nitric oxide pathways is essential.

In addition to its applications in drug development, this compound is also significant in the field of molecular biology, particularly in the design of inhibitors for specific enzymes. The ability to modify the structure of Na-Boc-Nw-nitro-D-arginine allows for the exploration of its pharmacological properties, providing a pathway for the creation of novel therapeutic agents. Its versatility and effectiveness in various applications make it a preferred choice for researchers looking to innovate in the fields of medicinal chemistry and biochemistry.

Synonyms
Boc-D-Arg(NO2)-OH
CAS Number
50913-12-7
Purity
≥ 99% (HPLC)
Molecular Formula
C11H21N5O6
Molecular Weight
319.3
MDL Number
MFCD00038091
Appearance
White powder
Optical Rotation
[α]D20 = +7.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-D-Arg(NO2)-OH
CAS Number
50913-12-7
Purity
≥ 99% (HPLC)
Molecular Formula
C11H21N5O6
Molecular Weight
319.3
MDL Number
MFCD00038091
Appearance
White powder
Optical Rotation
[α]D20 = +7.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nw-nitro-D-arginine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in synthesizing nitric oxide synthase inhibitors, which are crucial in developing treatments for cardiovascular diseases.
  • Biochemical Research: Researchers use it to study the role of nitric oxide in various physiological processes, helping to advance our understanding of cellular signaling pathways.
  • Drug Formulation: Its properties allow for the creation of more effective drug formulations, particularly in enhancing the bioavailability of therapeutic agents.
  • Peptide Synthesis: It is employed in the synthesis of modified peptides, which can lead to improved stability and activity of peptide-based drugs.
  • Academic Research: This compound is frequently used in academic settings for experiments related to enzyme inhibition and metabolic studies, providing valuable insights into enzyme mechanisms.

Citations