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Catalog Number:
01311
CAS Number:
23593-75-1
Clotrimazole
Purity:
≥ 99% (Assay)
Synonym(s):
1-(2-Chloro-α,α-diphenylbenzyl)imidazole, 1-(o-Chlorotrityl) imidazole
Antibiotic
Documents
$22.03 /1G
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Product Information

Clotrimazole is a potent antifungal agent widely recognized for its effectiveness in treating various fungal infections. This compound, characterized by its imidazole structure, is commonly utilized in both pharmaceutical formulations and topical applications. Clotrimazole works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting their integrity and leading to cell death. Its broad-spectrum activity makes it suitable for treating conditions such as athlete's foot, ringworm, and candidiasis.

In addition to its antifungal properties, Clotrimazole is also employed in the formulation of creams, ointments, and lozenges, making it a versatile choice for healthcare professionals. Its ability to provide rapid relief from symptoms and its low incidence of side effects enhance its appeal in clinical settings. Researchers and industry professionals appreciate Clotrimazole not only for its efficacy but also for its stability and compatibility with various excipients, facilitating its incorporation into diverse therapeutic products.

Synonyms
1-(2-Chloro-α,α-diphenylbenzyl)imidazole, 1-(o-Chlorotrityl) imidazole
CAS Number
23593-75-1
Purity
≥ 99% (Assay)
Molecular Formula
C22H17N2Cl
Molecular Weight
344.8
MDL Number
MFCD00057220
PubChem ID
2812
Melting Point
140-147 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
1-(2-Chloro-α,α-diphenylbenzyl)imidazole, 1-(o-Chlorotrityl) imidazole
CAS Number
23593-75-1
Purity
≥ 99% (Assay)
Molecular Formula
C22H17N2Cl
Molecular Weight
344.8
MDL Number
MFCD00057220
PubChem ID
2812
Melting Point
140-147 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Clotrimazole is widely utilized in research focused on:

  • Antifungal Treatments: Commonly used in topical creams and ointments for treating fungal infections like athlete's foot and ringworm, providing effective relief and promoting faster healing.
  • Pharmaceutical Formulations: Incorporated in various pharmaceutical products, enhancing the efficacy of medications due to its broad-spectrum antifungal properties, making it a staple in many formulations.
  • Veterinary Medicine: Applied in veterinary practices for treating fungal infections in animals, ensuring the health and well-being of pets and livestock.
  • Research on Drug Resistance: Used in laboratory settings to study mechanisms of antifungal resistance, helping researchers develop new strategies to combat resistant strains.
  • Cosmetic Applications: Included in some cosmetic products to prevent fungal infections, particularly in formulations for skin and nail care, offering an added layer of protection.

Citations