Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
00875
CAS Number:
3416-05-5
2',3'-Dideoxythymidine
Purity:
≥ 99% (UV, dry basis)
Synonym(s):
ddT
Documents
$80.50 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

2',3'-Dideoxythymidine, commonly referred to as ddT or d4T, is a nucleoside analog that plays a crucial role in antiviral therapies, particularly in the treatment of HIV. This compound is characterized by its unique structure, which allows it to inhibit viral replication by interfering with the reverse transcriptase enzyme, making it a vital component in antiretroviral regimens. Its ability to mimic natural nucleosides while lacking the 2' and 3' hydroxyl groups enhances its efficacy in disrupting the viral life cycle, thus providing a therapeutic advantage in managing HIV infections.

In addition to its primary application in HIV treatment, 2',3'-Dideoxythymidine has been explored for its potential in various research settings, including studies on viral resistance and the development of new antiviral agents. Its unique properties make it a valuable tool for researchers aiming to understand the mechanisms of viral replication and resistance. The compound's favorable pharmacokinetic profile and its compatibility with other antiretroviral drugs further enhance its utility in combination therapies, making it a preferred choice for healthcare professionals seeking effective treatment options for patients.

Synonyms
ddT
CAS Number
3416-05-5
Purity
≥ 99% (UV, dry basis)
Molecular Formula
C10H14N2O4
Molecular Weight
226.2
MDL Number
MFCD00010570
PubChem ID
5280
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
ddT
CAS Number
3416-05-5
Purity
≥ 99% (UV, dry basis)
Molecular Formula
C10H14N2O4
Molecular Weight
226.2
MDL Number
MFCD00010570
PubChem ID
5280
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2',3'-Dideoxythymidine is widely utilized in research focused on:

  • Antiviral Research: This compound is a key player in the development of antiretroviral therapies for HIV. It helps inhibit viral replication, making it essential for researchers developing effective treatments.
  • Pharmaceutical Development: Used in the formulation of drugs, it serves as a building block for creating nucleotide analogs, which can enhance the efficacy of antiviral medications.
  • Cell Culture Studies: In laboratory settings, it is employed to study the effects of nucleoside analogs on cellular processes, aiding researchers in understanding viral mechanisms and drug resistance.
  • Genetic Research: This compound is utilized in molecular biology to investigate DNA synthesis and repair mechanisms, providing insights into genetic disorders and potential therapeutic targets.
  • Clinical Trials: It plays a crucial role in clinical research for evaluating the safety and effectiveness of new antiviral drugs, contributing to advancements in treatment protocols for viral infections.

Citations