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Catalog Number:
00867
CAS Number:
50-91-9
5-Fluoro-2'-deoxyuridine
Purity:
≥ 99% (HPLC)
Synonym(s):
5-F-2'-dU, Floxuridine
Hazmat
Documents
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Product Information

5-Fluoro-2'-deoxyuridine is a fluorinated nucleoside analog that plays a crucial role in molecular biology and pharmaceutical research. This compound is particularly significant in the development of antiviral and anticancer therapies, as it acts as an inhibitor of DNA synthesis. Its unique structure allows it to interfere with the replication of viral and cancerous cells, making it a valuable tool in the treatment of various malignancies and viral infections. Researchers have utilized 5-Fluoro-2'-deoxyuridine in combination therapies to enhance the efficacy of existing treatments, demonstrating its potential to improve patient outcomes.

In addition to its therapeutic applications, 5-Fluoro-2'-deoxyuridine is also employed in laboratory settings for the study of nucleic acid metabolism and cellular processes. Its ability to mimic natural nucleosides while incorporating a fluorine atom provides insights into the mechanisms of drug resistance and cellular response to therapy. This compound's versatility and effectiveness make it an essential resource for researchers and industry professionals focused on advancing medical science and developing innovative treatment strategies.

Synonyms
5-F-2'-dU, Floxuridine
CAS Number
50-91-9
Purity
≥ 99% (HPLC)
Molecular Formula
C9H11FN2O5
Molecular Weight
246.19
MDL Number
MFCD00006530
PubChem ID
3363
Melting Point
145 - 153 °C
Appearance
White to almost white powder or crystalli
Conditions
Store at RT
General Information
Synonyms
5-F-2'-dU, Floxuridine
CAS Number
50-91-9
Purity
≥ 99% (HPLC)
Molecular Formula
C9H11FN2O5
Molecular Weight
246.19
MDL Number
MFCD00006530
PubChem ID
3363
Melting Point
145 - 153 °C
Appearance
White to almost white powder or crystalli
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Fluoro-2'-deoxyuridine is widely utilized in research focused on:

  • Antiviral Treatments: This compound is effective in treating viral infections, particularly in the context of HIV therapy, where it helps inhibit viral replication.
  • Cancer Research: It is used in the development of chemotherapy agents, targeting rapidly dividing cancer cells and improving treatment efficacy.
  • Genetic Studies: Researchers employ it in studies of DNA synthesis and repair mechanisms, providing insights into genetic mutations and their implications.
  • Pharmaceutical Development: The compound serves as a building block in the synthesis of other nucleoside analogs, enhancing the development of new antiviral and anticancer drugs.
  • Diagnostic Applications: It is utilized in molecular imaging techniques, aiding in the detection and monitoring of certain diseases through targeted imaging agents.

Citations