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Catalog Number:
00685
CAS Number:
47689-67-8
Boc-O-2-bromo-Z-L-tyrosine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Tyr(2-Br-Z)-OH
Documents
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Product Information

Boc-O-2-bromo-Z-L-tyrosine is a valuable compound widely utilized in peptide synthesis and pharmaceutical research. This derivative of tyrosine features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and reactivity during chemical reactions. Its unique structure allows for selective incorporation into peptides, making it an essential building block for the development of bioactive compounds and therapeutic agents. Researchers appreciate its role in synthesizing complex peptides that can be used in drug discovery, particularly in the development of targeted therapies and biologics.

The compound's bromine substituent provides additional reactivity, enabling further modifications that can enhance the biological activity of the resulting peptides. This versatility makes Boc-O-2-bromo-Z-L-tyrosine an attractive choice for chemists working in medicinal chemistry and biochemistry. Its applications extend to the synthesis of enzyme inhibitors, receptor ligands, and other biologically relevant molecules, showcasing its potential in advancing pharmaceutical research and development.

Synonyms
Boc-L-Tyr(2-Br-Z)-OH
CAS Number
47689-67-8
Purity
≥ 99% (HPLC)
Molecular Formula
C22H24BrNO7
Molecular Weight
494.35
MDL Number
MFCD00037098
PubChem ID
4293754
Melting Point
~ 120 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 8 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Tyr(2-Br-Z)-OH
CAS Number
47689-67-8
Purity
≥ 99% (HPLC)
Molecular Formula
C22H24BrNO7
Molecular Weight
494.35
MDL Number
MFCD00037098
PubChem ID
4293754
Melting Point
~ 120 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 8 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-O-2-bromo-Z-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, enabling researchers to create complex proteins for various studies, including drug development and biomolecular research.
  • Drug Development: Its unique structure allows for the modification of drug candidates, enhancing their efficacy and specificity. This is particularly valuable in the pharmaceutical industry where targeted therapies are essential.
  • Bioconjugation: The compound is used in bioconjugation processes, linking biomolecules to therapeutic agents. This application is crucial in developing antibody-drug conjugates, which improve the delivery of drugs to specific cells.
  • Research in Neuroscience: Boc-O-2-bromo-Z-L-tyrosine can be utilized in studies related to neurotransmitter activity, aiding researchers in understanding the role of tyrosine derivatives in brain function and disorders.
  • Analytical Chemistry: It is employed in analytical methods to quantify and analyze tyrosine derivatives in biological samples, providing insights into metabolic pathways and disease states.

Citations