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Catalog Number:
00495
CAS Number:
71989-38-3
Fmoc-O-tert-butyl-L-tyrosine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-L-Tyr(tBu)-OH
Documents
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Product Information

Fmoc-O-tert-butyl-L-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block in the production of complex peptides. Its tert-butyl group enhances solubility and stability, facilitating smoother reactions and improving yields. Researchers and industry professionals appreciate its application in solid-phase peptide synthesis, where it serves as a key component for constructing bioactive peptides and therapeutic agents.

In addition to its role in peptide synthesis, Fmoc-O-tert-butyl-L-tyrosine is also valuable in the development of pharmaceuticals and bioconjugates. Its unique structure allows for the incorporation of various functional groups, enabling the design of targeted drug delivery systems. The compound's stability and ease of handling make it a preferred choice for laboratories focused on peptide research and development. With its proven track record in enhancing peptide synthesis efficiency, Fmoc-O-tert-butyl-L-tyrosine stands out as a crucial reagent for advancing research in medicinal chemistry and biotechnology.

Synonyms
Fmoc-L-Tyr(tBu)-OH
CAS Number
71989-38-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C28H29NO5
Molecular Weight
459.5
MDL Number
MFCD00037129
PubChem ID
100112
Melting Point
145 - 162 °C
Appearance
White powder
Optical Rotation
[a]D20
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Tyr(tBu)-OH
CAS Number
71989-38-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C28H29NO5
Molecular Weight
459.5
MDL Number
MFCD00037129
PubChem ID
100112
Melting Point
145 - 162 °C
Appearance
White powder
Optical Rotation
[a]D20
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences efficiently.
  • Drug Development: It plays a significant role in pharmaceutical research, where it is used to develop peptide-based drugs, enhancing the bioavailability and stability of therapeutic agents.
  • Bioconjugation: The compound is utilized in bioconjugation processes, enabling researchers to attach biomolecules to drugs or imaging agents, which is crucial for targeted therapies and diagnostics.
  • Research in Neuroscience: Fmoc-O-tert-butyl-L-tyrosine is employed in studies related to neurotransmitter functions, helping scientists understand the role of tyrosine derivatives in brain chemistry.
  • Protein Engineering: It is used in the modification of proteins to study structure-function relationships, providing insights that can lead to the development of novel enzymes or therapeutic proteins.

Citations