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Catalog Number:
00381
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-lcaa-CPG
Synonym(s):
DMT-dA-NBz-lcaa-CPG, 500A, 20-40 µM/g
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$18.53 /1G
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-lcaa-CPG is a specialized nucleoside derivative that plays a crucial role in the field of molecular biology and biochemistry. This compound is particularly valuable for researchers involved in oligonucleotide synthesis and gene therapy applications. Its unique structure, featuring protective groups and a benzoyl moiety, enhances its stability and solubility, making it an ideal choice for the synthesis of modified nucleotides. This compound can be utilized in the development of antisense oligonucleotides and RNA interference technologies, where precise modifications are essential for effective gene regulation.

The presence of the dimethoxytrityl group allows for easy purification and characterization, while the benzoyl group provides additional protection during synthetic processes. This versatility not only streamlines the synthesis workflow but also improves the overall yield of high-quality nucleic acids. Researchers can leverage this compound to create innovative solutions in therapeutic development, diagnostics, and genetic engineering, thus expanding the horizons of molecular research and biotechnology.

Synonyms
DMT-dA-NBz-lcaa-CPG, 500A, 20-40 µM/g
MDL Number
MFCD01310319
Conditions
Store at 0-8°C
General Information
Synonyms
DMT-dA-NBz-lcaa-CPG, 500A, 20-40 µM/g
MDL Number
MFCD01310319
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-lcaa-CPG is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of oligonucleotides, which are essential for various genetic research applications, including gene editing and RNA interference.
  • Drug Development: It plays a significant role in the development of nucleoside analogs, which can be used in antiviral and anticancer therapies, providing targeted treatment options with potentially fewer side effects.
  • Biotechnology: The compound is employed in the production of modified nucleotides that enhance the stability and efficacy of therapeutic oligonucleotides, making them more effective in clinical applications.
  • Diagnostic Tools: It is utilized in the creation of probes and primers for PCR (Polymerase Chain Reaction), facilitating the detection of specific DNA sequences in various diagnostic tests.
  • Research Reagents: This chemical serves as a reagent in biochemical assays, aiding researchers in studying enzyme activity and nucleic acid interactions, which are crucial for understanding cellular processes.

Citations