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Catalog Number:
00379
5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-lcaa-CPG
Synonym(s):
DMT-dC-NBz-lcaa-CPG, 500A, 20-40 µM/g
Documents
$18.53 /5G
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-lcaa-CPG is a specialized nucleoside derivative that plays a crucial role in the field of molecular biology and biochemistry. This compound is particularly valuable for researchers involved in DNA synthesis and oligonucleotide production. Its unique structure, featuring protective groups, enhances stability and facilitates the efficient incorporation of nucleotides during synthetic processes. This makes it an ideal choice for applications in gene therapy, antisense oligonucleotide design, and other genetic engineering techniques.

The compound's ability to protect the nucleobase while allowing for selective reactions is a significant advantage, as it minimizes side reactions and increases yield during synthesis. Additionally, its compatibility with various coupling chemistries makes it versatile for different laboratory protocols. Researchers can leverage this compound to streamline their workflows, improve the quality of their synthesized oligonucleotides, and ultimately advance their projects in genomics and therapeutics.

Synonyms
DMT-dC-NBz-lcaa-CPG, 500A, 20-40 µM/g
Molecular Formula
C37H34N3O7X
Molecular Weight
632.69
MDL Number
MFCD01310318
Conditions
Store at RT
General Information
Synonyms
DMT-dC-NBz-lcaa-CPG, 500A, 20-40 µM/g
Molecular Formula
C37H34N3O7X
Molecular Weight
632.69
MDL Number
MFCD01310318
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-lcaa-CPG is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of oligonucleotides, which are essential for various genetic research applications, including gene editing and molecular diagnostics.
  • Drug Development: It is used in the development of nucleoside analogs, which can be crucial in creating antiviral and anticancer therapies, offering targeted treatment options with potentially fewer side effects.
  • Biotechnology: The compound plays a significant role in the production of DNA probes and primers, facilitating advancements in techniques like PCR (Polymerase Chain Reaction) that are vital for genetic analysis and cloning.
  • Research in Epigenetics: It is employed in studies investigating DNA methylation patterns, helping researchers understand gene regulation mechanisms and their implications in diseases.
  • Diagnostic Tools: This chemical is integral in developing assays for detecting specific DNA sequences, enhancing the accuracy of genetic testing and personalized medicine approaches.

Citations