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Catalog Number:
00301
CAS Number:
77-86-1
2-Amino-2-(hydroxymethyl)-1,3-propanediol
Grade:
Molecular biology grade
Purity:
≥ 99% (Assay by titration)
Synonym(s):
Tris(hydroxymethyl)aminomethane, Tris base, Trometamol
Documents
$20.20 /100G
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Product Information

2-Amino-2-(hydroxymethyl)-1,3-propanediol, commonly known as TRIS or tris(hydroxymethyl)aminomethane, is a versatile buffering agent widely utilized in biochemical and molecular biology applications. This compound is particularly valued for its ability to maintain a stable pH in biological systems, making it essential in various laboratory protocols, including protein purification, enzyme assays, and cell culture. Its unique properties allow it to function effectively across a broad range of pH levels, typically between 7.0 and 9.0, which is crucial for experiments requiring precise pH control.

Researchers and industry professionals appreciate TRIS for its low toxicity and compatibility with a variety of biological molecules, which enhances its utility in sensitive applications. Additionally, its role in formulating buffers for electrophoresis and chromatography underscores its importance in analytical chemistry. With its reliable performance and ease of use, TRIS remains a staple in laboratories, supporting advancements in research and development across multiple scientific disciplines.

Synonyms
Tris(hydroxymethyl)aminomethane, Tris base, Trometamol
CAS Number
77-86-1
Purity
≥ 99% (Assay by titration)
Grade
Molecular biology grade
Molecular Formula
C4H11NO3
Molecular Weight
121.1
MDL Number
MFCD00004679
PubChem ID
6503
Melting Point
168 - 172 °C
Appearance
White crystalline powder
Boiling Point
219 - 220 °C/10 mmHg (Lit.)
Conditions
Store at RT
General Information
Synonyms
Tris(hydroxymethyl)aminomethane, Tris base, Trometamol
CAS Number
77-86-1
Purity
≥ 99% (Assay by titration)
Grade
Molecular biology grade
Molecular Formula
C4H11NO3
Molecular Weight
121.1
MDL Number
MFCD00004679
PubChem ID
6503
Melting Point
168 - 172 °C
Appearance
White crystalline powder
Boiling Point
219 - 220 °C/10 mmHg (Lit.)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Amino-2-(hydroxymethyl)-1,3-propanediol is widely utilized in research focused on:

  • Biotechnology: This compound serves as a buffering agent in cell culture media, helping to maintain pH stability, which is crucial for the growth and viability of various cell types.
  • Pharmaceuticals: It is used as an excipient in drug formulations, enhancing the solubility and stability of active pharmaceutical ingredients, thereby improving drug efficacy.
  • Cosmetics: The compound acts as a moisturizing agent in skincare products, providing hydration and enhancing the texture of creams and lotions.
  • Laboratory Reagents: It is employed as a reagent in biochemical assays, facilitating various chemical reactions due to its ability to stabilize pH levels.
  • Food Industry: Used as a food additive, it helps in maintaining the quality and stability of food products, ensuring longer shelf life and better taste.

Citations