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Catalog Number:
00299
CAS Number:
1185-53-1
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
Purity:
≥ 98% (Assay)
Synonym(s):
Tris(hydroxymethyl)aminomethane hydrochloride, TRIS hydrochloride
Documents
$18.50 /25G
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Product Information

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride, commonly known as TRIS hydrochloride, is a versatile compound widely utilized in biochemical and molecular biology applications. This white crystalline powder is highly soluble in water, making it an ideal buffering agent for biological systems. Its unique ability to maintain a stable pH in the physiological range (around pH 7.0 to 9.0) makes it invaluable in various laboratory settings, particularly in the preparation of buffers for electrophoresis, enzyme assays, and cell culture media. Researchers often rely on TRIS hydrochloride for its low toxicity and compatibility with biological molecules, ensuring that experimental results are reliable and reproducible.

In addition to its buffering capabilities, TRIS hydrochloride is also employed in the formulation of pharmaceuticals and diagnostic reagents, where it helps to stabilize active ingredients and enhance product efficacy. Its role in protein purification and characterization further underscores its importance in research and development. With its broad applicability and favorable properties, TRIS hydrochloride remains a staple in laboratories, contributing to advancements in life sciences and biochemistry.

Synonyms
Tris(hydroxymethyl)aminomethane hydrochloride, TRIS hydrochloride
CAS Number
1185-53-1
Purity
≥ 98% (Assay)
Molecular Formula
C4H11NO3·HCl
Molecular Weight
157.6
MDL Number
MFCD00012590
PubChem ID
93573
Melting Point
150 - 156 °C (Lit.)
Appearance
White crystalline or fine white powder
Conditions
Store at RT
General Information
Synonyms
Tris(hydroxymethyl)aminomethane hydrochloride, TRIS hydrochloride
CAS Number
1185-53-1
Purity
≥ 98% (Assay)
Molecular Formula
C4H11NO3·HCl
Molecular Weight
157.6
MDL Number
MFCD00012590
PubChem ID
93573
Melting Point
150 - 156 °C (Lit.)
Appearance
White crystalline or fine white powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride is widely utilized in research focused on:

  • Biotechnology: This compound serves as a buffering agent in cell culture media, helping to maintain pH stability, which is crucial for the growth and maintenance of various cell lines.
  • Pharmaceuticals: It is used as an excipient in drug formulations, enhancing the solubility and stability of active pharmaceutical ingredients, thereby improving drug efficacy.
  • Cosmetics: The compound acts as a humectant in skincare products, helping to retain moisture and improve skin hydration, making it a popular choice in moisturizers and serums.
  • Research Laboratories: It is employed as a reagent in biochemical assays, particularly in studies involving enzyme activity and protein interactions, providing reliable results in experimental setups.
  • Food Industry: This chemical can be utilized as a food additive, where it functions as a stabilizer or thickener, enhancing the texture and shelf-life of various food products.

Citations