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Catalog Number:
00260
CAS Number:
13292-46-1
Rifampicin
Grade:
Meets USP Specification
Purity:
95 - 103% (Assay on dry basis)
Synonym(s):
3-(4-Methylpiperazinyliminomethyl)rifamycin SV, Rifampin, Rifamycin AMP
Antibiotic
Documents
$20.00 /1G
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Product Information

Rifampicin is a potent antibiotic renowned for its efficacy in treating a variety of bacterial infections, particularly tuberculosis and leprosy. This compound operates by inhibiting bacterial RNA synthesis, making it a critical agent in the fight against resistant strains of bacteria. Its unique structure, characterized by multiple hydroxyl and methoxy groups, enhances its solubility and bioavailability, allowing for effective therapeutic concentrations in the body. Researchers and healthcare professionals appreciate Rifampicin not only for its primary use in infectious disease treatment but also for its role in combination therapies, which can enhance the effectiveness of other antibiotics and reduce the likelihood of resistance development.

In addition to its medicinal applications, Rifampicin is also utilized in research settings to study bacterial resistance mechanisms and the development of new antimicrobial agents. Its versatility extends to various formulations, including oral and injectable forms, catering to different patient needs. The compound's ability to penetrate bacterial biofilms further underscores its significance in clinical settings, where biofilm-associated infections pose significant treatment challenges. With its proven track record and ongoing relevance in both clinical and research environments, Rifampicin remains a cornerstone in the arsenal against bacterial infections.

Synonyms
3-(4-Methylpiperazinyliminomethyl)rifamycin SV, Rifampin, Rifamycin AMP
CAS Number
13292-46-1
Purity
95 - 103% (Assay on dry basis)
Grade
Meets USP Specification
Molecular Formula
C43H58N4O12
Molecular Weight
823.0
MDL Number
MFCD00151389
PubChem ID
135512673
Appearance
Red-brown crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
3-(4-Methylpiperazinyliminomethyl)rifamycin SV, Rifampin, Rifamycin AMP
CAS Number
13292-46-1
Purity
95 - 103% (Assay on dry basis)
Grade
Meets USP Specification
Molecular Formula
C43H58N4O12
Molecular Weight
823.0
MDL Number
MFCD00151389
PubChem ID
135512673
Appearance
Red-brown crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Rifampicin is widely utilized in research focused on:

  • Tuberculosis Treatment: This antibiotic is a cornerstone in the treatment of tuberculosis (TB), effectively killing the bacteria responsible for the disease and preventing its spread.
  • Leprosy Management: Rifampicin is also used in combination therapies for leprosy, helping to reduce the bacterial load and improve patient outcomes.
  • Biofilm Disruption: In research settings, it is employed to study and disrupt biofilms formed by bacteria, which is crucial for understanding chronic infections and developing new treatment strategies.
  • Drug Interaction Studies: It serves as a model compound in pharmacokinetic studies to evaluate drug interactions, particularly in understanding how drugs affect liver enzymes.
  • Research on Antimicrobial Resistance: Rifampicin is pivotal in studies aimed at understanding and combating antimicrobial resistance, providing insights into how bacteria adapt to antibiotic treatments.

Citations