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Catalog Number:
00147
CAS Number:
82911-69-1
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
Purity:
≥ 98.5% (HPLC)
Synonym(s):
Fmoc-OSu, 9-Fluorenylmethyl-N-succinimidyl carbonate
Hazmat
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Product Information

N-(9-Fluorenylmethoxycarbonyloxy)succinimide is a versatile chemical compound widely utilized in organic synthesis and peptide chemistry. This compound serves as a protecting group for amines, enabling chemists to selectively modify functional groups without interference. Its unique structure allows for easy removal under mild conditions, making it an ideal choice for researchers aiming to streamline their synthetic pathways. The compound's stability and compatibility with various reaction conditions enhance its appeal in the development of pharmaceuticals and biologically active molecules.

In addition to its role in protecting group chemistry, N-(9-Fluorenylmethoxycarbonyloxy)succinimide is also employed in the synthesis of complex organic molecules, including natural products and drug candidates. Its application in solid-phase peptide synthesis has proven particularly beneficial, as it facilitates the efficient assembly of peptides with high purity and yield. Researchers and industry professionals can leverage this compound to enhance their synthetic strategies, ultimately leading to more efficient and effective product development.

Synonyms
Fmoc-OSu, 9-Fluorenylmethyl-N-succinimidyl carbonate
CAS Number
82911-69-1
Purity
≥ 98.5% (HPLC)
Molecular Formula
C19H15NO5
Molecular Weight
337.3
MDL Number
MFCD00010733
PubChem ID
134122
Melting Point
147 - 155 °C
Appearance
White or off-white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-OSu, 9-Fluorenylmethyl-N-succinimidyl carbonate
CAS Number
82911-69-1
Purity
≥ 98.5% (HPLC)
Molecular Formula
C19H15NO5
Molecular Weight
337.3
MDL Number
MFCD00010733
PubChem ID
134122
Melting Point
147 - 155 °C
Appearance
White or off-white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-(9-Fluorenylmethoxycarbonyloxy)succinimide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in peptide synthesis, allowing chemists to selectively modify amino acids without interfering with other functional groups. This enhances the efficiency and specificity of the synthesis process.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds by facilitating the formation of stable intermediates. This stability is essential for ensuring the efficacy and safety of new drugs.
  • Bioconjugation: The compound is used in bioconjugation techniques, where it helps in attaching biomolecules to surfaces or other molecules. This is particularly valuable in creating targeted drug delivery systems and diagnostic tools.
  • Research in Organic Chemistry: It is a key reagent in various organic synthesis reactions, enabling researchers to explore new chemical pathways and develop innovative materials with unique properties.
  • Polymer Chemistry: The compound is utilized in the synthesis of polymers, contributing to the development of advanced materials with tailored characteristics for applications in coatings, adhesives, and more.

Citations