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Catalog Number:
00128
CAS Number:
24424-99-5
Di-tert-butyl pyrocarbonate
Purity:
≥ 99% (GC)
Synonym(s):
Boc anhydride, Di-tert-butyl dicarbonate, Pyrocarbonic acid di-tert-butyl ester
Hazmat
Documents
$18.53 /25G
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Product Information

Reagent for the preparation of Boc-amino acids and peptides in high yields.

Synonyms
Boc anhydride, Di-tert-butyl dicarbonate, Pyrocarbonic acid di-tert-butyl ester
CAS Number
24424-99-5
Purity
≥ 99% (GC)
Molecular Formula
C10H18O5
Molecular Weight
0
MDL Number
MFCD00008805
PubChem ID
90495
Melting Point
20 - 25 °C
Density
0.95 g/cm3
Appearance
Colorless liquid or white crystal
Boiling Point
56 - 57 °C/0.5mmHg
Refractive Index
1.41
Conditions
Store at 0 - 8 °C
Warnings
Danger
General Information
Synonyms
Boc anhydride, Di-tert-butyl dicarbonate, Pyrocarbonic acid di-tert-butyl ester
CAS Number
24424-99-5
Purity
≥ 99% (GC)
Molecular Formula
C10H18O5
Molecular Weight
0
MDL Number
MFCD00008805
PubChem ID
90495
Melting Point
20 - 25 °C
Density
0.95 g/cm3
Appearance
Colorless liquid or white crystal
Boiling Point
56 - 57 °C/0.5mmHg
Refractive Index
1.41
Conditions
Store at 0 - 8 °C
Warnings
Danger
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
Danger
Applications

Di-tert-butyl pyrocarbonate is widely utilized in research focused on:

  • Protecting Groups in Organic Synthesis: This compound serves as an effective protecting group for amines and alcohols, allowing chemists to selectively modify other functional groups without interference.
  • Pharmaceutical Development: It plays a crucial role in the synthesis of pharmaceutical intermediates, enhancing the efficiency of drug development processes by providing better yields and purities.
  • Polymer Chemistry: Used in the production of polymers, it helps in the modification of polymer properties, leading to materials with enhanced thermal and mechanical stability.
  • Bioconjugation Techniques: In biochemistry, it is employed in bioconjugation methods, facilitating the attachment of biomolecules to surfaces or other molecules, which is vital for developing biosensors and drug delivery systems.
  • Analytical Chemistry: This compound is also utilized in analytical methods, such as chromatography, where it aids in the derivatization of analytes, improving detection sensitivity and specificity.

Citations