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Catalog Number:
00118
CAS Number:
40615-36-9
4,4'-Dimethoxytrityl chloride
Purity:
≥ 99% (HPLC)
Synonym(s):
DMT·Cl, 4,4'-Dimethoxy-triphenylchloromethane
Documents
$32.75 /25G
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Product Information

4,4'-Dimethoxytrityl chloride is a versatile reagent widely utilized in organic synthesis, particularly in the field of nucleic acid chemistry. This compound serves as a protective group for hydroxyl functionalities, making it invaluable in the synthesis of oligonucleotides and other complex biomolecules. Its ability to selectively protect and deprotect hydroxyl groups allows researchers to manipulate molecular structures with precision, facilitating the development of novel therapeutic agents and diagnostic tools.

With its unique structure, 4,4'-Dimethoxytrityl chloride offers enhanced stability and reactivity compared to similar protective groups, making it a preferred choice for chemists looking to optimize their synthetic pathways. Its applications extend beyond nucleic acids, finding utility in the synthesis of various pharmaceuticals and fine chemicals. Researchers and industry professionals can leverage this compound to streamline their workflows, improve yields, and achieve higher purity in their final products.

Synonyms
DMT·Cl, 4,4'-Dimethoxy-triphenylchloromethane
CAS Number
40615-36-9
Purity
≥ 99% (HPLC)
Molecular Formula
C21H19O2Cl
Molecular Weight
338.83
MDL Number
MFCD00008409
PubChem ID
96831
Melting Point
118 - 126 ?C
Appearance
Peach or light pink color powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
DMT·Cl, 4,4'-Dimethoxy-triphenylchloromethane
CAS Number
40615-36-9
Purity
≥ 99% (HPLC)
Molecular Formula
C21H19O2Cl
Molecular Weight
338.83
MDL Number
MFCD00008409
PubChem ID
96831
Melting Point
118 - 126 ?C
Appearance
Peach or light pink color powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4,4'-Dimethoxytrityl chloride is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This chemical serves as a protecting group in the synthesis of oligonucleotides, ensuring that specific nucleobases remain unreacted during chemical reactions.
  • Pharmaceutical Development: It is crucial in the development of nucleoside analogs, which can lead to new antiviral and anticancer drugs, enhancing therapeutic options.
  • Organic Synthesis: Used in various organic reactions, it helps in the construction of complex molecules, making it valuable for chemists in academia and industry.
  • Biotechnology: In the production of RNA-based therapeutics, it aids in the modification of RNA molecules, improving their stability and efficacy.
  • Research Laboratories: Its role in protecting functional groups allows researchers to conduct multi-step synthesis with high precision, leading to more efficient experimental outcomes.

Citations