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Catalog Number:
00115
CAS Number:
11024-24-1
Digitonin
Purity:
≥ 50% (TLC)
Synonym(s):
Digitin
Hazmat
Documents
$113.87 /100MG
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Product Information

Digitonin is a natural glycoside derived from the plant Digitalis purpurea, known for its unique structure and properties. This compound is widely recognized for its ability to selectively solubilize membrane proteins, making it an invaluable tool in biochemistry and molecular biology. Researchers utilize Digitonin for cell lysis and membrane permeabilization, facilitating the extraction of proteins and other biomolecules for further analysis. Its effectiveness in disrupting lipid bilayers while maintaining the integrity of protein complexes sets it apart from other detergents, providing a more gentle approach to studying membrane-associated proteins.

In addition to its applications in research, Digitonin is also used in various pharmaceutical formulations and as a biochemical reagent. Its role in the study of ion channels and transporters highlights its importance in pharmacological research. The compound's ability to enhance the solubility of certain compounds can lead to improved bioavailability in drug development. Overall, Digitonin stands out for its versatility and effectiveness, making it a preferred choice for professionals in the fields of biochemistry, pharmacology, and biotechnology.

Synonyms
Digitin
CAS Number
11024-24-1
Purity
≥ 50% (TLC)
Molecular Formula
C56H92O29
Molecular Weight
1229.34
MDL Number
MFCD00077729
PubChem ID
409778
Melting Point
230 - 240 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -53 ± 4° (C=1 in ethanol)
Conditions
Store at RT
General Information
Synonyms
Digitin
CAS Number
11024-24-1
Purity
≥ 50% (TLC)
Molecular Formula
C56H92O29
Molecular Weight
1229.34
MDL Number
MFCD00077729
PubChem ID
409778
Melting Point
230 - 240 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -53 ± 4° (C=1 in ethanol)
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Digitonin is widely utilized in research focused on:

  • Biochemical Research: It is commonly used as a tool for studying membrane proteins and their interactions, particularly in the isolation and purification of membrane-bound enzymes.
  • Pharmaceutical Applications: Digitonin serves as a natural detergent in drug formulation, enhancing the solubility and bioavailability of poorly soluble compounds, which is crucial in developing effective medications.
  • Cell Biology: Researchers employ digitonin to selectively permeabilize cell membranes, allowing for the study of intracellular processes without disrupting overall cell integrity.
  • Analytical Chemistry: It is used in assays to quantify cholesterol levels in biological samples, providing a reliable method for assessing lipid metabolism and related health conditions.
  • Plant Research: Digitonin helps in extracting and analyzing chlorophyll and other pigments from plant tissues, aiding in studies related to photosynthesis and plant health.

Citations