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Catalog Number:
00110
CAS Number:
693-13-0
N,N'-Diisopropylcarbodiimide
Purity:
≥ 99% (Assay)
Synonym(s):
DIC
Hazmat
Documents
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Product Information

Diisopropylcarbodiimide (DIC) is a colorless to pale yellow liquid reagent used as a dehydrating agent in organic synthesis. It is particularly noted for its role in the synthesis of amides, esters, and peptides, offering advantages in reactions where steric hindrance is a concern.

Synonyms
DIC
CAS Number
693-13-0
Purity
≥ 99% (Assay)
Molecular Formula
C7H14N2
Molecular Weight
126.2
MDL Number
MFCD00065689
Density
0.810 - 0.814 g/mL
Appearance
Colorless to white transparent liquid
Boiling Point
145 - 148 °C
Refractive Index
n20/D 1.42 - 1.44
Conditions
Store at RT
Warnings
Danger
General Information
Synonyms
DIC
CAS Number
693-13-0
Purity
≥ 99% (Assay)
Molecular Formula
C7H14N2
Molecular Weight
126.2
MDL Number
MFCD00065689
Density
0.810 - 0.814 g/mL
Appearance
Colorless to white transparent liquid
Boiling Point
145 - 148 °C
Refractive Index
n20/D 1.42 - 1.44
Conditions
Store at RT
Warnings
Danger
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
Danger
Applications

Diisopropylcarbodiimide (DIC) is a colorless to pale yellow liquid reagent used as a dehydrating agent in organic synthesis. 

  • Peptide and Amide Formation: Used in peptide coupling reactions to synthesize proteins and peptides.
  • Ester Formation: Facilitates the synthesis of esters from alcohols and carboxylic acids.
  • Less Sterically Hindered Reactions: Ideal for reactions that require a milder, less hindered reagent than DCC.
  • Pharmaceutical and Fine Chemical Synthesis: Essential in developing various bioactive molecules.

Citations