Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
00059
CAS Number:
82473-24-3
3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
Purity:
98 - 100% (HPLC)
Synonym(s):
CHAPSO
Documents
$25.00 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate, commonly known as CHAPS, is a zwitterionic detergent widely utilized in biochemical and molecular biology applications. This compound is particularly effective for solubilizing membrane proteins and stabilizing protein complexes, making it an essential tool in protein purification and analysis. Its unique properties allow for the maintenance of protein functionality while minimizing denaturation, which is crucial for researchers working with sensitive biomolecules. CHAPS is also employed in various applications such as gel electrophoresis, where it aids in the separation of proteins based on size and charge, and in the preparation of samples for mass spectrometry.

In addition to its role in protein research, CHAPS has shown potential in pharmaceutical formulations, particularly in enhancing drug solubility and bioavailability. Its ability to form micelles makes it an excellent candidate for drug delivery systems, providing a pathway for improved therapeutic efficacy. Researchers and industry professionals appreciate CHAPS for its versatility and effectiveness, making it a valuable addition to any laboratory focused on protein studies or drug formulation.

Synonyms
CHAPSO
CAS Number
82473-24-3
Purity
98 - 100% (HPLC)
Molecular Formula
C32H58N2O8S
Molecular Weight
630.89
MDL Number
MFCD00081079
PubChem ID
3253738
Appearance
White powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
CHAPSO
CAS Number
82473-24-3
Purity
98 - 100% (HPLC)
Molecular Formula
C32H58N2O8S
Molecular Weight
630.89
MDL Number
MFCD00081079
PubChem ID
3253738
Appearance
White powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate is widely utilized in research focused on:

  • Biotechnology: This compound is commonly used as a surfactant in cell lysis and protein extraction processes, facilitating the release of proteins from cells for further analysis.
  • Pharmaceutical Development: It aids in drug formulation by enhancing the solubility and stability of active pharmaceutical ingredients, making it easier to develop effective medications.
  • Membrane Studies: Researchers use it to study membrane dynamics and interactions, particularly in understanding how drugs and other compounds penetrate biological membranes.
  • Diagnostics: This chemical is employed in diagnostic assays, improving the sensitivity and specificity of tests by enhancing the detection of biomolecules.
  • Cosmetic Industry: It is included in formulations for skin and hair products, acting as a stabilizer and emulsifier, which helps improve product texture and performance.

Citations