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Catalog Number:
00036
CAS Number:
54631-81-1
Boc-O-benzyl-L-trans-4-hydroxyproline
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Hyp(Bzl)-OH
Documents
$37.96 /1G
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Product Information

Boc-O-benzyl-L-trans-4-hydroxyproline is a versatile amino acid derivative that plays a significant role in peptide synthesis and pharmaceutical development. This compound is particularly valued for its ability to serve as a protecting group in the synthesis of complex peptides, allowing for the selective modification of amino acids without compromising the integrity of the overall structure. Its unique structure enhances stability and solubility, making it an ideal choice for researchers focused on drug design and development.

In addition to its applications in synthetic chemistry, Boc-O-benzyl-L-trans-4-hydroxyproline is also utilized in the production of biologically active compounds, including those with potential therapeutic effects. Its compatibility with various coupling reagents and its ability to facilitate the formation of peptide bonds make it a preferred choice among chemists and biochemists. The compound's properties not only streamline the synthesis process but also improve yields, making it an essential tool for professionals in the pharmaceutical and biotechnology industries.

Synonyms
Boc-L-Hyp(Bzl)-OH
CAS Number
54631-81-1
Purity
≥ 98% (HPLC)
Molecular Formula
C17H23NO5
Molecular Weight
321.38
MDL Number
MFCD00037325
Appearance
White to off-white powder
Optical Rotation
[α]D25 = -40 ± 2º (C=2 in EtOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Hyp(Bzl)-OH
CAS Number
54631-81-1
Purity
≥ 98% (HPLC)
Molecular Formula
C17H23NO5
Molecular Weight
321.38
MDL Number
MFCD00037325
Appearance
White to off-white powder
Optical Rotation
[α]D25 = -40 ± 2º (C=2 in EtOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-O-benzyl-L-trans-4-hydroxyproline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly those requiring specific stereochemistry. Its unique structure allows for the introduction of hydroxyl groups, enhancing the stability and functionality of the resultant peptides.
  • Drug Development: In pharmaceutical research, it is used to create novel drug candidates, especially in the development of treatments for conditions like cancer and neurological disorders. Its ability to mimic natural amino acids makes it an attractive option for designing biologically active compounds.
  • Material Science: The compound is applied in the development of advanced materials, including hydrogels and polymers. Its properties can improve the mechanical strength and biocompatibility of these materials, making them suitable for biomedical applications.
  • Biotechnology: Researchers utilize it in the modification of proteins and enzymes, enhancing their activity or stability. This is particularly beneficial in industrial biotechnology, where optimized enzymes can lead to more efficient processes.
  • Analytical Chemistry: It is employed as a standard in various analytical methods, aiding in the quantification and characterization of complex mixtures. This application is crucial for ensuring the accuracy and reliability of experimental results.

Citations