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Catalog Number:
00035
CAS Number:
13836-37-8
Boc-Arg(Tos)-OH
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-Nω-4-toluenesulfonyl-L-arginine
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Product Information

Na-Boc-Nw-4-toluenesulfonyl-L-arginine is a versatile compound widely utilized in peptide synthesis and biochemistry. This protected arginine derivative features a Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for researchers working on complex peptide sequences. Its unique sulfonyl group allows for selective reactions, facilitating the development of novel peptides with tailored properties.

This compound is particularly valuable in the pharmaceutical industry for the synthesis of bioactive peptides and drug candidates. Researchers can leverage its properties to create peptides with improved pharmacokinetic profiles or to explore new therapeutic avenues. Additionally, its compatibility with various coupling reagents and conditions makes it a preferred choice for chemists aiming to streamline their synthesis processes. With its robust performance and adaptability, Na-Boc-Nw-4-toluenesulfonyl-L-arginine stands out as a crucial tool for advancing peptide research and development.

Synonyms
Boc-Nω-4-toluenesulfonyl-L-arginine
CAS Number
13836-37-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H28N4O6S
Molecular Weight
428.5
MDL Number
MFCD00065557
PubChem ID
294909
Appearance
White powder
Optical Rotation
[a]D20 = -3.5 ± 1 º (C=4 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-Nω-4-toluenesulfonyl-L-arginine
CAS Number
13836-37-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H28N4O6S
Molecular Weight
428.5
MDL Number
MFCD00065557
PubChem ID
294909
Appearance
White powder
Optical Rotation
[a]D20 = -3.5 ± 1 º (C=4 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nw-4-toluenesulfonyl-L-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interference from other functional groups. This is particularly beneficial in the pharmaceutical industry for creating complex peptide-based drugs.
  • Bioconjugation: It is used in bioconjugation processes, where biomolecules are linked to other molecules, enhancing the development of targeted drug delivery systems. This application is crucial in the field of biotechnology and personalized medicine.
  • Enzyme Inhibition Studies: Researchers utilize this compound to study enzyme inhibition mechanisms, providing insights into metabolic pathways and potential therapeutic targets, which is vital for drug discovery.
  • Diagnostic Reagents: The compound can be employed as a reagent in diagnostic tests, particularly in assays that require specific binding interactions, thus improving the accuracy of medical diagnostics.
  • Research on Protein Interactions: It aids in the investigation of protein-protein interactions, helping scientists understand cellular processes and disease mechanisms, which is essential for developing new therapeutic strategies.

Citations