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Catalog Number:
48164
Fmoc-Tyr(tBu)-Aib-OH
Purity:
≥ 95%
Synonym(s):
Acide Fmoc-O-(tert-butyl)-L-tyrosinyl-á-aminoisobutyrique
Documents
$30.00 /100 mg
Taille
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Informations sur le produit

Fmoc-Tyr(tBu)-Aib-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethyloxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of the amino group during solid-phase peptide synthesis. The presence of the t-butyl (tBu) side chain enhances the compound's hydrophobicity, making it particularly useful in the synthesis of peptides that require specific folding or stability. Additionally, the incorporation of Aib (α-aminoisobutyric acid) contributes to the formation of helical structures, which are crucial in the design of biologically active peptides.

Researchers and industry professionals can leverage Fmoc-Tyr(tBu)-Aib-OH in various applications, including the development of peptide-based therapeutics, vaccine candidates, and biomaterials. Its unique properties allow for the fine-tuning of peptide sequences to achieve desired biological activities, making it an invaluable tool in medicinal chemistry and biochemistry. Whether you are working on drug discovery or exploring new peptide formulations, this compound offers the reliability and performance needed for successful outcomes.

Formule moléculaire
C32H36N2O6
Poids moléculaire 
544.6
Rotation optique 
[a] D 20 = -13,3 ± 5 ° (C = 1 MeOH)
Informations générales
Formule moléculaire
C32H36N2O6
Poids moléculaire 
544.6
Rotation optique 
[a] D 20 = -13,3 ± 5 ° (C = 1 MeOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-Tyr(tBu)-Aib-OH is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences.
  • Drug Development: It is used in the development of peptide-based drugs, where its unique properties can enhance the efficacy and stability of therapeutic peptides.
  • Bioconjugation: The compound can be employed in bioconjugation techniques, aiding in the attachment of peptides to various biomolecules for targeted drug delivery systems.
  • Research in Neuroscience: Fmoc-Tyr(tBu)-Aib-OH is utilized in studies related to neuropeptides, contributing to the understanding of neurotransmitter functions and interactions.
  • Protein Engineering: It plays a role in protein engineering, where modifications can be made to enhance protein stability and functionality, particularly in therapeutic applications.

Citations