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Catalog Number:
47371
CAS Number:
54573-75-0
Doxercalciférol
Purity:
≥ 98 % (HPLC)
Synonym(s):
(5 Z ,7 E ,22 E )-9,10-Secoergosta-5,7,10,22-tétraène-1,3-diol
Hazmat
Documents
$320.40 /5 mg
Taille
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Informations sur le produit

Doxercalciferol is a synthetic form of vitamin D2, primarily utilized in the management of secondary hyperparathyroidism in patients with chronic kidney disease. This compound is known for its ability to regulate calcium and phosphate metabolism, making it essential in the treatment of conditions related to bone health and mineral balance. Doxercalciferol is particularly beneficial for patients undergoing dialysis, as it helps to mitigate the risk of bone disorders associated with renal failure.

In addition to its therapeutic applications, Doxercalciferol is also being explored in research settings for its potential role in various metabolic disorders. Its unique structure allows for effective binding to vitamin D receptors, enhancing its efficacy compared to other vitamin D analogs. This makes it a valuable compound for both clinical and research purposes, providing a reliable option for healthcare professionals aiming to improve patient outcomes in bone health management.

Numéro CAS 
54573-75-0
Formule moléculaire
C28H44O2
Poids moléculaire 
0
Point de fusion 
139 - 141 °C
Indice de réfraction 
1.540
Rotation optique 
[a] D 20 = 45 - 50 ° (C = 0,5 dans l'éthanol)
Informations générales
Numéro CAS 
54573-75-0
Formule moléculaire
C28H44O2
Poids moléculaire 
0
Point de fusion 
139 - 141 °C
Indice de réfraction 
1.540
Rotation optique 
[a] D 20 = 45 - 50 ° (C = 0,5 dans l'éthanol)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Doxercalciferol is widely utilized in research focused on:

  • Chronic Kidney Disease Management: This compound is primarily used to manage secondary hyperparathyroidism in patients with chronic kidney disease, helping to regulate calcium and phosphate levels effectively.
  • Bone Health Research: Researchers study its effects on bone mineralization and density, making it valuable in osteoporosis studies and treatments aimed at improving bone health.
  • Endocrine System Studies: Doxercalciferol plays a crucial role in research related to vitamin D metabolism and its effects on the endocrine system, providing insights into hormonal regulation.
  • Pharmaceutical Development: It is an important compound in the development of new medications targeting vitamin D deficiency, offering potential advantages over traditional vitamin D therapies.
  • Clinical Trials: Frequently used in clinical trials to evaluate its efficacy and safety in various patient populations, contributing to evidence-based medicine and improved patient outcomes.

Citations