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Catalog Number:
43996
Chlorure de 3-(4-nitrophényl)-5-méthyl-2-phényltétrazolium
Purity:
≥ 98 % (HPLC)
Synonym(s):
Chlorure de 2-phényl-3-(4-nitrophényl)-5-méthyltétrazolium
Hazmat
Documents
$126.79 /100 mg
Taille
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Product Information

3-(4-Nitrophenyl)-5-methyl-2-phenyltetrazolium chloride is a versatile chemical compound widely utilized in biochemical research and analytical applications. This compound, often referred to as MTT, is particularly valued for its role in cell viability assays, where it serves as a colorimetric indicator of metabolic activity in living cells. The reduction of MTT to formazan crystals by viable cells allows researchers to quantitatively assess cell proliferation and cytotoxicity, making it an essential tool in pharmacological studies and toxicology assessments.

In addition to its applications in cell biology, 3-(4-Nitrophenyl)-5-methyl-2-phenyltetrazolium chloride is also employed in various fields such as microbiology and cancer research, where it aids in evaluating the effects of drugs on cell growth. Its unique ability to provide a visual and measurable output makes it superior to other viability assays, offering researchers a reliable and efficient method for analyzing cellular responses. This compound's compatibility with high-throughput screening processes further enhances its utility in drug discovery and development.

Synonyms
Chlorure de 2-phényl-3-(4-nitrophényl)-5-méthyltétrazolium
Purity
≥ 98 % (HPLC)
Molecular Formula
C14H12ClN5O2
Molecular Weight
317.73
MDL Number
MFCD00060011
Appearance
Poudre blanche à jaune à cristal
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Chlorure de 2-phényl-3-(4-nitrophényl)-5-méthyltétrazolium
Purity
≥ 98 % (HPLC)
Molecular Formula
C14H12ClN5O2
Molecular Weight
317.73
MDL Number
MFCD00060011
Appearance
Poudre blanche à jaune à cristal
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Oui
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

3-(4-Nitrophenyl)-5-methyl-2-phenyltetrazolium chloride is widely utilized in research focused on:

  • Cell Viability Assays: This compound is commonly used in MTT assays to evaluate cell proliferation and cytotoxicity, providing researchers with reliable data on drug efficacy.
  • Biochemical Research: It serves as a colorimetric reagent for detecting metabolic activity in various biological samples, helping scientists understand cellular processes.
  • Pharmaceutical Development: In drug formulation studies, it aids in assessing the effectiveness of new compounds against specific cell lines, streamlining the drug discovery process.
  • Environmental Monitoring: The compound can be applied in studies assessing the impact of pollutants on microbial activity, offering insights into environmental health.
  • Food Safety Testing: It is utilized in assays that determine the viability of microorganisms in food products, ensuring safety and compliance with health standards.

Citations