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Catalog Number:
42218
CAS Number:
130495-35-1
SKF-96365
Purity:
≥ 98 % (HPLC)
Synonym(s):
1-[2-(4-méthoxyphényl)-2-[3-(4-méthoxyphényl)propoxy]éthyl]-1 H -imidazolehydrochlorure
Documents
$217.63 /10 mg
Taille
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Informations sur le produit

SKF-96365 is a potent and selective inhibitor of the TRPC (transient receptor potential canonical) channels, making it a valuable tool in various research applications. This compound has garnered attention for its role in studying calcium signaling pathways, particularly in the context of cellular processes such as proliferation, differentiation, and apoptosis. Researchers have utilized SKF-96365 to investigate its effects on neuronal activity and its potential neuroprotective properties, which could lead to advancements in treatments for neurodegenerative diseases. Additionally, its ability to modulate ion channel activity positions it as a promising candidate in pharmacological studies aimed at understanding cardiovascular and metabolic disorders.

The unique structure of SKF-96365, featuring a methoxyphenyl group, enhances its specificity and efficacy compared to other TRPC inhibitors, providing researchers with a reliable option for experimental applications. Its versatility extends to various fields, including pharmacology, neuroscience, and cell biology, making it an essential compound for professionals seeking to explore the intricate mechanisms of cellular signaling. With its established role in advancing scientific knowledge, SKF-96365 is an indispensable asset for laboratories focused on innovative research.

Numéro CAS 
130495-35-1
Formule moléculaire
C22H26N2O3 · HCl
Poids moléculaire 
402.92
Point de fusion 
119 °C
Informations générales
Numéro CAS 
130495-35-1
Formule moléculaire
C22H26N2O3 · HCl
Poids moléculaire 
402.92
Point de fusion 
119 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

SKF-96365 is widely utilized in research focused on:

  • Neuroscience Research: This compound is often used to study calcium signaling pathways in neurons, helping researchers understand various neurological disorders.
  • Pharmacology: SKF-96365 serves as a tool for investigating the effects of ion channels on cellular activities, which is crucial for drug development targeting cardiovascular and neurological diseases.
  • Cancer Research: Its application in cancer studies allows scientists to explore the role of calcium influx in tumor growth and metastasis, providing insights for potential therapeutic strategies.
  • Cardiovascular Studies: The compound is used to assess the impact of calcium channel blockers, aiding in the development of treatments for heart diseases.
  • Cell Biology: SKF-96365 helps in understanding the mechanisms of cell proliferation and differentiation, which is essential for tissue engineering and regenerative medicine.

Citations