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Catalog Number:
42198
CAS Number:
179324-69-7
Bortézomib
Purity:
≥ 98 % (HPLC)
Synonym(s):
Acide ( R -3-méthyl-1-[( S -3-phényl-2-(pyrazine-2-carboxamido)propanamido]butylboronique
Documents
$136.00 /10 mg
Taille
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Informations sur le produit

Bortezomib is a potent proteasome inhibitor widely recognized for its critical role in cancer therapy, particularly in the treatment of multiple myeloma and certain types of lymphoma. This compound functions by disrupting the proteasome's activity, leading to the accumulation of pro-apoptotic factors and ultimately inducing cancer cell death. Its unique mechanism of action has made it a cornerstone in targeted cancer treatments, offering significant benefits over traditional chemotherapy by specifically targeting malignant cells while sparing normal tissues.

In addition to its primary use in oncology, Bortezomib is also being explored for its potential applications in various other therapeutic areas, including autoimmune diseases and neurodegenerative disorders. Researchers appreciate its ability to modulate cellular pathways, making it a valuable tool in drug development and clinical research. With its established efficacy and ongoing studies, Bortezomib continues to hold promise for advancing cancer treatment and improving patient outcomes.

Numéro CAS 
179324-69-7
Formule moléculaire
C19H25BN4O4
Poids moléculaire 
384.24
Point de fusion 
123 °C
Rotation optique 
a 20 D = -55 à -50 ° (C=1 dans MeOH)
Informations générales
Numéro CAS 
179324-69-7
Formule moléculaire
C19H25BN4O4
Poids moléculaire 
384.24
Point de fusion 
123 °C
Rotation optique 
a 20 D = -55 à -50 ° (C=1 dans MeOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Bortezomib is widely utilized in research focused on:

  • Cancer Treatment: Primarily used in the treatment of multiple myeloma and certain types of lymphoma, Bortezomib inhibits proteasome activity, leading to cancer cell death.
  • Drug Development: Researchers are exploring Bortezomib’s potential in combination therapies to enhance efficacy against resistant cancer strains, making it a key compound in oncology drug research.
  • Biomarker Studies: It serves as a valuable tool in identifying biomarkers for cancer progression and treatment response, aiding in personalized medicine approaches.
  • Neurodegenerative Disease Research: Bortezomib is being investigated for its effects on neurodegenerative diseases, such as Alzheimer's, due to its ability to modulate protein degradation pathways.
  • Veterinary Medicine: There is ongoing research into the use of Bortezomib in treating certain cancers in animals, providing insights into its broader applications beyond human medicine.

Citations