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Catalog Number:
42170
CAS Number:
183322-45-4
PD 153035 Chlorhydrate
Purity:
≥ 98 % (HPLC)
Synonym(s):
Chlorhydrate de N- (3-bromophényl)-6,7-diméthoxy-4-quinazolinamine, Chlorhydrate de 4-[(3-bromophényl)amino]-6,7-diméthoxyquinazoline
Hazmat
Documents
$113.87 /25 mg
Taille
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Informations sur le produit

PD 153035 Hydrochloride is a potent and selective inhibitor of the epidermal growth factor receptor (EGFR), making it a valuable compound in cancer research and therapeutic development. This compound is particularly relevant in studies focused on the treatment of various malignancies, including non-small cell lung cancer and head and neck cancers, where EGFR plays a critical role in tumor growth and progression. Researchers utilize PD 153035 Hydrochloride to explore its efficacy in inhibiting tumor cell proliferation and inducing apoptosis, providing insights into potential combination therapies that enhance treatment outcomes.

In addition to its applications in oncology, PD 153035 Hydrochloride serves as a crucial tool in pharmacological studies aimed at understanding the signaling pathways involved in cell growth and differentiation. Its unique ability to selectively target EGFR allows for the investigation of downstream effects in cellular processes, making it an essential compound for researchers in the fields of molecular biology and pharmacology. By incorporating PD 153035 Hydrochloride into experimental designs, scientists can develop more effective therapeutic strategies and contribute to advancements in personalized medicine.

Numéro CAS 
183322-45-4
Formule moléculaire
C16H14BrN3O2 · HCl
Poids moléculaire 
396.67
Point de fusion 
265 °C (lit.)
Informations générales
Numéro CAS 
183322-45-4
Formule moléculaire
C16H14BrN3O2 · HCl
Poids moléculaire 
396.67
Point de fusion 
265 °C (lit.)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

PD 153035 Hydrochloride is widely utilized in research focused on:

  • Cancer Research: This compound acts as a selective inhibitor of certain receptor tyrosine kinases, making it valuable for studying tumor growth and progression in various cancer types.
  • Neuroscience: It is used to investigate the role of specific signaling pathways in neuronal function, helping researchers understand neurodegenerative diseases.
  • Pharmacology: PD 153035 Hydrochloride is employed in drug development studies to evaluate its efficacy and safety as a potential therapeutic agent.
  • Cell Biology: This compound aids in elucidating cell signaling mechanisms, providing insights into cellular responses to external stimuli.
  • Biotechnology: It is applied in the development of targeted therapies, offering a pathway for creating more effective treatments with fewer side effects compared to traditional chemotherapy.

Citations