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Catalog Number:
40201
CAS Number:
779331-47-4
Acide 2-benzyloxy-5-fluorophénylboronique
Purity:
97 - 105 % (dosage par titrage)
Synonym(s):
Acide 2-benzyloxy-5-fluorobenzèneboronique
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Product Information

2-Benzyloxy-5-fluorophenylboronic acid is a versatile compound widely utilized in pharmaceutical and chemical research. This boronic acid derivative is recognized for its unique ability to form reversible covalent bonds with diols, making it an essential building block in the synthesis of complex organic molecules. Its fluorine substitution enhances its reactivity and selectivity, which is particularly beneficial in drug discovery and development processes. Researchers often leverage this compound in the creation of targeted therapies, especially in oncology, where precision and efficacy are paramount.

In addition to its applications in medicinal chemistry, 2-Benzyloxy-5-fluorophenylboronic acid serves as a critical reagent in cross-coupling reactions, such as Suzuki-Miyaura coupling, facilitating the formation of carbon-carbon bonds. This property is invaluable for synthesizing various biochemicals and agrochemicals, providing a pathway for the development of novel compounds with enhanced biological activity. Its stability and ease of handling further position it as a preferred choice for researchers seeking reliable and effective reagents in their synthetic endeavors.

Synonyms
Acide 2-benzyloxy-5-fluorobenzèneboronique
CAS Number
779331-47-4
Purity
97 - 105 % (dosage par titrage)
Molecular Formula
C 13 H 12 BFO 3
Molecular Weight
246.04
MDL Number
MFCD03788403
PubChem ID
2782666
Appearance
Poudre cristalline blanche à blanc cassé
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Acide 2-benzyloxy-5-fluorobenzèneboronique
CAS Number
779331-47-4
Purity
97 - 105 % (dosage par titrage)
Molecular Formula
C 13 H 12 BFO 3
Molecular Weight
246.04
MDL Number
MFCD03788403
PubChem ID
2782666
Appearance
Poudre cristalline blanche à blanc cassé
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

2-Benzyloxy-5-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a critical intermediate in the synthesis of various pharmaceuticals, particularly in developing anti-cancer agents. Its unique structure allows for targeted modifications that enhance drug efficacy.
  • Organic Synthesis: It is frequently employed in organic synthesis as a boronic acid derivative, facilitating cross-coupling reactions. This application is particularly valuable in creating complex organic molecules used in agrochemicals and fine chemicals.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, due to its ability to form stable complexes with various substrates, enhancing material properties.
  • Bioconjugation: In biochemistry, it plays a role in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential for creating biosensors and drug delivery systems.
  • Fluorescent Probes: Its fluorine atom makes it suitable for use in fluorescent probes, aiding in imaging and tracking biological processes in live cells, which is crucial for understanding cellular mechanisms.

Citations