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Catalog Number:
38380
CAS Number:
364622-82-2
Doripénème monohydraté
Purity:
≥ 98 % (HPLC)
Synonym(s):
Acide (4R,5S,6S)-6-[(1R)-1-hydroxyéthyl]-4-méthyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)méthyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ène-2-carboxylique
Documents
$339.31 /50 mg
Taille
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Informations sur le produit

Doripenem monohydrate is a broad-spectrum carbapenem antibiotic known for its potent antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria, including multidrug-resistant strains. This compound is particularly valuable in clinical settings for treating serious infections such as pneumonia, urinary tract infections, and intra-abdominal infections. Its unique structure enhances its stability against beta-lactamases, making it an effective choice for combating resistant bacterial infections. Researchers and healthcare professionals appreciate Doripenem monohydrate for its efficacy and safety profile, which allows for its use in various patient populations, including those with compromised immune systems.

In addition to its clinical applications, Doripenem monohydrate is also utilized in pharmaceutical research and development, where it serves as a benchmark for developing new antibiotics. Its ability to penetrate bacterial cell walls effectively makes it a subject of interest in studies aimed at understanding antibiotic resistance mechanisms. The compound's favorable pharmacokinetic properties, including its distribution and elimination, further enhance its utility in both therapeutic and research contexts, making it a vital asset in the ongoing fight against bacterial infections.

Numéro CAS 
364622-82-2
Formule moléculaire
C15H24N4O6S2 · H2O
Poids moléculaire 
438.52
Point de fusion 
173 °C (déc.)
Rotation optique 
32 - 37 ° (C=1, H2O)
Informations générales
Numéro CAS 
364622-82-2
Formule moléculaire
C15H24N4O6S2 · H2O
Poids moléculaire 
438.52
Point de fusion 
173 °C (déc.)
Rotation optique 
32 - 37 ° (C=1, H2O)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Doripenem monohydrate is widely utilized in research focused on:

  • Antibiotic Development: This compound is a broad-spectrum antibiotic effective against various bacterial infections, making it crucial for developing new treatments in the pharmaceutical industry.
  • Clinical Applications: Used in hospital settings for treating severe infections, particularly in patients with compromised immune systems, it helps improve patient outcomes and reduce hospital stays.
  • Combination Therapies: Often combined with other antibiotics to enhance efficacy against resistant bacterial strains, it provides a strategic advantage in tackling complex infections.
  • Research in Microbiology: Employed in laboratory studies to understand bacterial resistance mechanisms, aiding researchers in developing more effective antibiotics.
  • Pharmacokinetics Studies: Used in drug formulation research to evaluate absorption and distribution in the body, helping optimize dosing regimens for better therapeutic effects.

Citations