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Catalog Number:
38363
CAS Number:
19545-26-7
Wortmannin
Purity:
≥ 98 % (HPLC)
Synonym(s):
KY 12420
Hazmat
Documents
$294.24 /20 mg
Taille
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Informations sur le produit
Numéro CAS 
19545-26-7
Formule moléculaire
C23H24O8
Poids moléculaire 
0
Point de fusion 
235 - 239 °C
Rotation optique 
85 - 89 ° (C=0,17, CHCl3)
Informations générales
Numéro CAS 
19545-26-7
Formule moléculaire
C23H24O8
Poids moléculaire 
0
Point de fusion 
235 - 239 °C
Rotation optique 
85 - 89 ° (C=0,17, CHCl3)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Wortmannin is widely utilized in research focused on various applications:

  • Cancer Research: This compound is a potent inhibitor of phosphoinositide 3-kinase (PI3K), making it valuable in studying cancer cell signaling pathways. Researchers use it to explore potential treatments for various cancers by understanding how PI3K inhibition affects tumor growth.
  • Neuroscience: Wortmannin is employed to investigate the role of PI3K in neuronal survival and differentiation. Its application helps in understanding neurodegenerative diseases and developing neuroprotective strategies.
  • Cardiovascular Studies: By inhibiting PI3K, this compound aids in exploring its effects on cardiac function and signaling pathways, which can lead to new insights into heart diseases and potential therapeutic targets.
  • Immunology: Researchers utilize wortmannin to study immune cell signaling and function. Its ability to modulate immune responses makes it a useful tool in developing treatments for autoimmune diseases.
  • Drug Development: As a research tool, wortmannin helps in the screening of new drug candidates targeting PI3K pathways. Its specificity allows scientists to better understand the mechanisms of action of potential therapeutics.

Citations