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Catalog Number:
38308
CAS Number:
147127-20-6
Ténofovir
Purity:
97 - 101 % (HPLC)
Synonym(s):
Acide ( R )-[[2-(6-amino-9 H -purine-9-yl)-1-méthyléthoxy]méthyl]phosphonique, ( R )-PMPA,( R )-9-(2-phosphonométhoxypropyl)adénine
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Product Information

Tenofovir is a potent antiviral compound primarily used in the treatment of HIV and hepatitis B infections. As a nucleotide reverse transcriptase inhibitor (NRTI), it works by interfering with the replication of viral DNA, thereby reducing the viral load in patients. Its unique structure allows for effective incorporation into viral DNA, making it a critical component of combination therapy regimens. Tenofovir is recognized for its favorable safety profile and has been extensively studied, demonstrating significant efficacy in clinical trials.

In addition to its primary applications in antiviral therapy, Tenofovir is also being explored for potential use in pre-exposure prophylaxis (PrEP) to prevent HIV transmission in high-risk populations. Its versatility and effectiveness make it a valuable asset in both clinical and research settings, providing healthcare professionals with a reliable option for managing viral infections. Researchers continue to investigate its potential in various therapeutic contexts, underscoring its relevance in modern medicine.

Synonyms
Acide ( R )-[[2-(6-amino-9 H -purine-9-yl)-1-méthyléthoxy]méthyl]phosphonique, ( R )-PMPA,( R )-9-(2-phosphonométhoxypropyl)adénine
CAS Number
147127-20-6
Purity
97 - 101 % (HPLC)
Molecular Formula
C9H14N5O4P
Molecular Weight
287.22
MDL Number
MFCD00943794
PubChem ID
64987
Melting Point
282 - 284 °C (lit.)
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -19 à -23 °
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Acide ( R )-[[2-(6-amino-9 H -purine-9-yl)-1-méthyléthoxy]méthyl]phosphonique, ( R )-PMPA,( R )-9-(2-phosphonométhoxypropyl)adénine
CAS Number
147127-20-6
Purity
97 - 101 % (HPLC)
Molecular Formula
C9H14N5O4P
Molecular Weight
287.22
MDL Number
MFCD00943794
PubChem ID
64987
Melting Point
282 - 284 °C (lit.)
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -19 à -23 °
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Tenofovir is widely utilized in research focused on:

  • Antiviral Treatments: It is a key component in medications for treating HIV and hepatitis B, helping to suppress viral replication and improve patient outcomes.
  • Pre-Exposure Prophylaxis (PrEP): Used in preventive therapies, Tenofovir significantly reduces the risk of HIV transmission among high-risk populations, making it a vital tool in public health strategies.
  • Research on Drug Resistance: Scientists study Tenofovir to understand and combat drug-resistant strains of HIV, enhancing treatment protocols and patient care.
  • Combination Therapies: Often combined with other antiretroviral drugs, Tenofovir enhances the efficacy of treatment regimens, providing a more robust approach to managing HIV infections.
  • Pharmacokinetic Studies: Researchers utilize Tenofovir to explore its absorption, distribution, metabolism, and excretion, helping to optimize dosing strategies for better therapeutic outcomes.

Citations