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Catalog Number:
38299
CAS Number:
144701-48-4
Telmisartan
Grade:
conforme aux spécifications USP, NF
Purity:
98 - 102 % (dosage, sur une base sèche)
Synonym(s):
Acide 4'-[[4-méthyl-6-(1-méthyl-1 H -benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl]méthyl]biphényl-2-carboxylique, BIBR 277
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Informations sur le produit

Telmisartan is a potent angiotensin II receptor antagonist primarily used in the management of hypertension and cardiovascular diseases. This compound is recognized for its ability to effectively lower blood pressure by inhibiting the action of angiotensin II, a hormone that constricts blood vessels. Its unique structure allows for a longer duration of action compared to other antihypertensive agents, making it a preferred choice for patients requiring sustained blood pressure control. Additionally, Telmisartan has shown promise in improving insulin sensitivity and may offer protective benefits against certain cardiovascular complications, making it a valuable option in the treatment of metabolic syndrome.

In the pharmaceutical industry, Telmisartan is often utilized in combination therapies to enhance efficacy and patient compliance. Its favorable pharmacokinetic profile allows for once-daily dosing, which is advantageous for both patients and healthcare providers. Researchers are also exploring its potential applications in nephrology, particularly in protecting renal function in diabetic patients. With its established safety profile and versatility in treatment regimens, Telmisartan stands out as a key player in modern hypertension management.

Numéro CAS 
144701-48-4
Formule moléculaire
C33H30N4O2
Poids moléculaire 
514.63
Point de fusion 
268 - 270 °C
Informations générales
Numéro CAS 
144701-48-4
Formule moléculaire
C33H30N4O2
Poids moléculaire 
514.63
Point de fusion 
268 - 270 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Telmisartan is widely utilized in research focused on:

  • Hypertension Management: Commonly prescribed for lowering blood pressure, it helps reduce the risk of heart disease and stroke, making it essential in cardiology.
  • Diabetes Protection: Research shows that it may offer protective benefits for diabetic patients by improving insulin sensitivity and reducing cardiovascular risks.
  • Heart Failure Treatment: Used in combination therapies, it aids in managing heart failure symptoms, improving quality of life for patients.
  • Kidney Protection: Effective in slowing the progression of kidney disease in patients with hypertension or diabetes, it is crucial in nephrology.
  • Research on Angiotensin Receptor Blockade: Its mechanism is studied for developing new treatments for various cardiovascular and renal conditions, providing insights into innovative therapies.

Citations