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Catalog Number:
38239
CAS Number:
162011-90-7
Rofécoxib
Purity:
≥ 98% (CG)
Synonym(s):
4-[4-(méthylsulfonyl)phényl]-3-phényl-2(5 H )-furanone
Documents
$124.99 /250 mg
Taille
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Informations sur le produit

Rofecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor, primarily recognized for its anti-inflammatory and analgesic properties. This compound is widely utilized in the pharmaceutical industry for the management of pain and inflammation associated with conditions such as arthritis and acute pain episodes. Its unique mechanism of action allows for effective pain relief while minimizing gastrointestinal side effects commonly associated with non-steroidal anti-inflammatory drugs (NSAIDs). Rofecoxib's efficacy in reducing inflammation makes it a valuable option for researchers exploring new therapeutic pathways in pain management and inflammatory diseases.

In addition to its clinical applications, Rofecoxib has been the subject of extensive research, highlighting its potential in various therapeutic areas, including cardiovascular health and cancer treatment. Its ability to selectively inhibit COX-2 without affecting COX-1 provides a significant advantage over traditional NSAIDs, making it a preferred choice in specific patient populations. With ongoing studies and interest in its applications, Rofecoxib continues to hold promise for future developments in pain management and inflammatory disease treatment.

Numéro CAS 
162011-90-7
Formule moléculaire
C17H14O4S
Poids moléculaire 
314.36
Point de fusion 
207 - 211 °C
Informations générales
Numéro CAS 
162011-90-7
Formule moléculaire
C17H14O4S
Poids moléculaire 
314.36
Point de fusion 
207 - 211 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Rofecoxib is widely utilized in research focused on:

  • Pain Management: Commonly used in clinical settings for its effectiveness in alleviating pain, particularly in conditions like arthritis. Its selective inhibition of COX-2 enzymes helps reduce inflammation with fewer gastrointestinal side effects compared to traditional NSAIDs.
  • Cardiovascular Research: Investigated for its potential impact on cardiovascular health, Rofecoxib has been studied for its role in managing pain without significantly increasing cardiovascular risks, making it a subject of interest for heart disease research.
  • Pharmaceutical Development: Used as a reference compound in the development of new analgesics and anti-inflammatory drugs, helping researchers understand the mechanisms of action and improve drug efficacy.
  • Veterinary Medicine: Applied in veterinary practices to manage pain and inflammation in animals, showcasing its versatility beyond human medicine and providing relief in various species.
  • Clinical Trials: Frequently featured in clinical trials aimed at evaluating new treatment protocols for chronic pain conditions, offering insights into patient responses and long-term outcomes.

Citations