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Catalog Number:
38232
CAS Number:
135062-02-1
Répaglinide
Purity:
≥ 98 % (dosage par titration, HPLC)
Synonym(s):
Acide ( S )-(+)-2-éthoxy-4-[ N -[1-(2-pipéridinophényl)-3-méthyl-1-butyl]aminocarbonylméthyl]benzoïque, Prandin
Documents
$172.36 /200 mg
Taille
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Informations sur le produit

Repaglinide is a potent and rapid-acting oral hypoglycemic agent primarily used in the management of type 2 diabetes mellitus. As a member of the meglitinide class, it functions by stimulating insulin secretion from the pancreas, particularly after meals, thereby helping to control postprandial blood glucose levels. This unique mechanism makes Repaglinide particularly beneficial for patients who experience spikes in blood sugar after eating. Its quick onset of action allows for flexible dosing, making it an ideal choice for individuals who may have irregular eating patterns or prefer to tailor their medication to their meal schedule.

In addition to its primary use in diabetes management, Repaglinide has been explored in various research settings for its potential role in combination therapies, enhancing glycemic control when used alongside other antidiabetic medications. Its favorable pharmacokinetic profile, characterized by a short half-life, allows for easy adjustment of doses based on individual patient needs. This adaptability, combined with its efficacy, positions Repaglinide as a valuable option for healthcare professionals seeking to optimize diabetes treatment plans for their patients.

Numéro CAS 
135062-02-1
Formule moléculaire
C27H36N2O4
Poids moléculaire 
452.6
Point de fusion 
131 - 135 °C
Rotation optique 
[a] D 20 = 7 - 10 ° (C = 1 dans MeOH)
Informations générales
Numéro CAS 
135062-02-1
Formule moléculaire
C27H36N2O4
Poids moléculaire 
452.6
Point de fusion 
131 - 135 °C
Rotation optique 
[a] D 20 = 7 - 10 ° (C = 1 dans MeOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Repaglinide is widely utilized in research focused on:

  • Diabetes Management: Primarily used as an oral medication to control blood sugar levels in patients with type 2 diabetes, offering a rapid onset of action that helps manage post-meal glucose spikes effectively.
  • Pharmaceutical Development: Researchers explore its pharmacokinetics and pharmacodynamics to improve formulations and develop combination therapies, enhancing treatment options for diabetes.
  • Clinical Trials: Frequently involved in clinical studies assessing the efficacy and safety of new diabetes treatments, providing valuable data for regulatory approvals.
  • Comparative Effectiveness Research: Used in studies comparing the effectiveness of various diabetes medications, helping healthcare providers make informed treatment decisions.
  • Patient Adherence Studies: Investigated in research aimed at understanding patient adherence to diabetes therapies, as its dosing flexibility can improve compliance among patients.

Citations