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Catalog Number:
38121
CAS Number:
31430-18-9
Nocodazole
Purity:
≥ 98 % (HPLC)
Synonym(s):
Méthyl[5-(2-thiénylcarbonyl)-1 H -benzimidazol-2-yl]carbamate
Documents
$220.33 /25 mg
Taille
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Informations sur le produit

Nocodazole is a potent microtubule inhibitor widely utilized in research and pharmaceutical applications. Known for its ability to disrupt microtubule dynamics, Nocodazole plays a crucial role in cell cycle studies, particularly in the investigation of mitosis and cellular processes. Its unique structure allows it to effectively inhibit cell division, making it an invaluable tool for researchers studying cancer biology and drug resistance mechanisms. Additionally, Nocodazole has been employed in various assays to assess the effects of microtubule stabilization and destabilization, providing insights into cellular behavior and therapeutic strategies.

In the pharmaceutical industry, Nocodazole's properties extend to potential applications in developing anti-cancer therapies, where its ability to induce cell cycle arrest can enhance the efficacy of other treatments. Researchers appreciate Nocodazole for its specificity and effectiveness, which can lead to more targeted and less toxic treatment options compared to traditional chemotherapeutics. Its versatility and effectiveness in both in vitro and in vivo studies make Nocodazole a preferred choice for professionals seeking reliable results in their experimental designs.

Numéro CAS 
31430-18-9
Formule moléculaire
C14H11N3O3S
Poids moléculaire 
301.32
Point de fusion 
259 - 161 °C (déc.)
Informations générales
Numéro CAS 
31430-18-9
Formule moléculaire
C14H11N3O3S
Poids moléculaire 
301.32
Point de fusion 
259 - 161 °C (déc.)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Nocodazole is widely utilized in research focused on:

  • Cell Cycle Studies: This compound is a potent microtubule inhibitor, making it invaluable for researchers studying the cell cycle and mitosis. By disrupting microtubule dynamics, it helps in understanding cellular processes and the effects of various drugs on cell division.
  • Cancer Research: Nocodazole is frequently used in cancer studies to investigate the mechanisms of tumor growth and metastasis. Its ability to halt cell division allows scientists to explore potential therapeutic strategies for targeting cancer cells.
  • Neuroscience: In neuroscience, nocodazole is employed to study neuronal transport mechanisms. By inhibiting microtubule function, researchers can gain insights into neurodegenerative diseases and the role of cytoskeletal dynamics in neuronal health.
  • Drug Development: Pharmaceutical companies utilize nocodazole in the early stages of drug development to screen for compounds that can effectively target microtubule dynamics, leading to the discovery of new anti-cancer agents.
  • Genetic Studies: It is also applied in genetic research to synchronize cells at specific phases of the cell cycle, allowing for more accurate analysis of gene expression and function during different stages of cellular activity.

Citations