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Catalog Number:
38109
CAS Number:
82956-11-4
Mésylate de nafamostat
Purity:
≥ 98 % (HPLC)
Synonym(s):
6-Amidino-2-naphtyl 4-guanidinobenzoate Bis(méthanesulfonate), Acide 4-guanidinobenzoïque 6-amidino-2-naphthyl ester bis(méthanesulfonate)
Documents
$68.20 /20 mg
Taille
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Informations sur le produit

Nafamostat mesylate is a potent synthetic serine protease inhibitor, primarily recognized for its application in the treatment of various medical conditions, including pancreatitis and as an antiviral agent. This compound has garnered attention for its ability to inhibit the activity of several proteases, making it a valuable tool in both clinical and research settings. Its unique mechanism of action allows for the modulation of inflammatory responses, which is particularly beneficial in managing acute and chronic inflammatory diseases. Researchers have also explored its potential in the treatment of COVID-19, where it has shown promise in inhibiting viral entry into host cells.

In addition to its therapeutic applications, Nafamostat mesylate is utilized in laboratory settings for studying protease functions and their roles in various biological processes. Its effectiveness in modulating protease activity makes it an essential compound for researchers investigating the mechanisms of disease and potential therapeutic interventions. With its multifaceted applications, Nafamostat mesylate stands out as a critical compound for both clinical and research purposes, offering significant benefits in the fields of medicine and biochemistry.

Numéro CAS 
82956-11-4
Formule moléculaire
C19H17N5O2 · 2CH4O3S
Poids moléculaire 
539.58
Point de fusion 
257 - 259 °C
Informations générales
Numéro CAS 
82956-11-4
Formule moléculaire
C19H17N5O2 · 2CH4O3S
Poids moléculaire 
539.58
Point de fusion 
257 - 259 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Nafamostat mesylate is widely utilized in research focused on:

  • Antiviral Therapy: This compound is effective against various viruses, including coronaviruses, making it a valuable candidate in the development of antiviral medications.
  • Thrombolytic Applications: Nafamostat is used in the treatment of acute pancreatitis and other conditions requiring rapid anticoagulation, providing a quick response in critical care settings.
  • Research on Blood Coagulation: It serves as a tool for studying coagulation pathways, helping researchers understand blood clotting mechanisms and potential treatments for clotting disorders.
  • Kidney Protection: In renal research, it has shown promise in protecting kidney cells from damage during ischemic events, which is crucial for developing therapies for kidney diseases.
  • Drug Development: Its unique properties allow researchers to explore new formulations and combinations in drug development, particularly in the fields of oncology and infectious diseases.

Citations