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Catalog Number:
38094
CAS Number:
54527-84-3
Chlorhydrate de nicardipine
Grade:
USP
Purity:
98 - 102 % (dosage, sur une base sèche)
Synonym(s):
Chlorhydrate de méthyl 2-[méthyl(phénylméthyl)amino]éthyl ester d'acide 1,4-dihydro-2,6-diméthyl-4-(3-nitrophényl)-3,5-pyridinedicarboxylique
Hazmat
Documents
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Taille
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Product Information

Nicardipine hydrochloride is a potent calcium channel blocker primarily utilized in the management of hypertension and angina pectoris. This compound works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Its unique structure allows for effective targeting of L-type calcium channels, making it a preferred choice in clinical settings for patients requiring precise blood pressure control.

In addition to its cardiovascular applications, Nicardipine hydrochloride has shown promise in various research contexts, including studies on cerebral vasospasm and as a potential therapeutic agent in neuroprotection. Its ability to cross the blood-brain barrier opens avenues for further exploration in treating neurological conditions. With a favorable pharmacokinetic profile, including rapid absorption and a relatively short half-life, this compound is ideal for both acute and chronic management of cardiovascular conditions. Researchers and healthcare professionals can rely on Nicardipine hydrochloride for its efficacy and versatility in therapeutic applications.

Synonyms
Chlorhydrate de méthyl 2-[méthyl(phénylméthyl)amino]éthyl ester d'acide 1,4-dihydro-2,6-diméthyl-4-(3-nitrophényl)-3,5-pyridinedicarboxylique
CAS Number
54527-84-3
Purity
98 - 102 % (dosage, sur une base sèche)
Grade
USP
Molecular Formula
C26H29N3O6 · HCl
Molecular Weight
515.99
MDL Number
MFCD00057327
PubChem ID
41114
Appearance
Poudre cristalline jaune ou jaune clair
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Chlorhydrate de méthyl 2-[méthyl(phénylméthyl)amino]éthyl ester d'acide 1,4-dihydro-2,6-diméthyl-4-(3-nitrophényl)-3,5-pyridinedicarboxylique
CAS Number
54527-84-3
Purity
98 - 102 % (dosage, sur une base sèche)
Grade
USP
Molecular Formula
C26H29N3O6 · HCl
Molecular Weight
515.99
MDL Number
MFCD00057327
PubChem ID
41114
Appearance
Poudre cristalline jaune ou jaune clair
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Oui
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Nicardipine hydrochloride is widely utilized in research focused on:

  • Cardiovascular Medicine: This compound is primarily used as a medication to treat high blood pressure and angina. It works by relaxing blood vessels, which improves blood flow and reduces the heart's workload.
  • Hypertensive Emergencies: In acute medical settings, nicardipine is administered intravenously to manage severe hypertension, providing rapid control of blood pressure in critical situations.
  • Research on Calcium Channel Blockers: Researchers study nicardipine to understand its effects on calcium channels, which can lead to the development of new cardiovascular therapies and improved treatment protocols.
  • Pharmaceutical Formulations: The compound is also explored in the formulation of sustained-release medications, enhancing patient compliance by reducing the frequency of dosing.
  • Comparative Studies: Nicardipine is often compared with other antihypertensive agents in clinical trials, providing insights into its efficacy and safety profile, which can guide treatment choices in various patient populations.

Citations