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Catalog Number:
38088
CAS Number:
53-19-0
Mitotane
Purity:
≥ 98% (CG)
Synonym(s):
1-(2-chlorophényl)-1-(4-chlorophényl)-2,2-dichloroéthane, o,p'-DDD
Documents
$116.67 /1G
Taille
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Informations sur le produit

Mitotane is a potent pharmaceutical compound primarily utilized in the treatment of adrenocortical carcinoma, a rare form of cancer affecting the adrenal glands. With its unique structure, Mitotane exhibits selective cytotoxicity towards adrenal cortex cells, making it an essential agent in oncology. Its mechanism of action involves the disruption of adrenal steroidogenesis, leading to decreased cortisol production, which is crucial for managing hypercortisolism in patients. Researchers and healthcare professionals value Mitotane for its ability to improve patient outcomes in cases where conventional therapies may fall short.

In addition to its primary use in cancer treatment, Mitotane has shown potential in research settings, particularly in studies focused on adrenal function and steroid metabolism. Its unique properties allow for targeted therapeutic strategies, providing a significant advantage over other compounds in similar applications. As a result, Mitotane is not only a critical component in the clinical management of specific cancers but also a valuable tool for advancing scientific understanding in endocrinology and oncology.

Numéro CAS 
53-19-0
Formule moléculaire
C 14 H 10 Cl 4
Poids moléculaire 
320.03
Point de fusion 
76 - 80 °C
Informations générales
Numéro CAS 
53-19-0
Formule moléculaire
C 14 H 10 Cl 4
Poids moléculaire 
320.03
Point de fusion 
76 - 80 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Mitotane is widely utilized in research focused on:

  • Adrenocortical Carcinoma Treatment: It is primarily used in the treatment of adrenal gland cancer, helping to reduce tumor size and manage symptoms effectively.
  • Hormonal Regulation Studies: Researchers use Mitotane to study its effects on hormone production, particularly cortisol, providing insights into adrenal function and disorders.
  • Drug Interaction Research: It serves as a model compound in pharmacology to investigate interactions with other medications, enhancing understanding of drug metabolism and safety profiles.
  • Animal Models in Oncology: Mitotane is employed in preclinical studies using animal models to evaluate new therapies for adrenal tumors, aiding in the development of innovative treatments.
  • Clinical Trials: It plays a crucial role in clinical trials aimed at improving treatment protocols for adrenal cancer, offering potential benefits over traditional therapies.

Citations