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Catalog Number:
38040
CAS Number:
595-33-5
Acétate de mégestrol
Purity:
≥ 96 % (HPLC)
Synonym(s):
17-acétate de mégestrol, 17-acétate de 17a-hydroxy-6-méthyl-4,6-prégnadiène-3,20-dione
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Product Information

Megestrol acetate is a synthetic progestin that plays a crucial role in various therapeutic applications, particularly in the management of hormone-related conditions. This compound is widely recognized for its effectiveness in treating anorexia, cachexia, and significant weight loss in patients with cancer or AIDS. Its ability to stimulate appetite and promote weight gain makes it a valuable option in palliative care settings. Additionally, megestrol acetate is utilized in hormone replacement therapy and as part of treatment regimens for certain types of breast and endometrial cancers, showcasing its versatility in oncology.

With its unique structure, megestrol acetate offers advantages over other progestins, including a favorable side effect profile and enhanced potency. Researchers and healthcare professionals appreciate its role in improving the quality of life for patients facing severe weight loss and its potential in hormone-sensitive cancers. As a trusted compound in both clinical and research settings, megestrol acetate continues to be a vital tool in the fight against debilitating conditions.

Synonyms
17-acétate de mégestrol, 17-acétate de 17a-hydroxy-6-méthyl-4,6-prégnadiène-3,20-dione
CAS Number
595-33-5
Purity
≥ 96 % (HPLC)
Molecular Formula
C24H32O4
Molecular Weight
384.52
MDL Number
MFCD00056470
PubChem ID
4048
Melting Point
213 - 220 °C
Appearance
Poudre blanche à presque blanche à cristal
Optical Rotation
[a] D 20 = 9 - 13 ° (C=2 dans CHCl3)
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
17-acétate de mégestrol, 17-acétate de 17a-hydroxy-6-méthyl-4,6-prégnadiène-3,20-dione
CAS Number
595-33-5
Purity
≥ 96 % (HPLC)
Molecular Formula
C24H32O4
Molecular Weight
384.52
MDL Number
MFCD00056470
PubChem ID
4048
Melting Point
213 - 220 °C
Appearance
Poudre blanche à presque blanche à cristal
Optical Rotation
[a] D 20 = 9 - 13 ° (C=2 dans CHCl3)
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Megestrol acetate is widely utilized in research focused on:

  • Appetite Stimulation: Commonly used in patients with severe weight loss due to chronic illnesses, it helps to stimulate appetite and promote weight gain, making it valuable in oncology and geriatrics.
  • Hormonal Therapy: Employed in the treatment of hormone-sensitive cancers, particularly breast and endometrial cancers, it acts as a progestin, providing an alternative to traditional therapies.
  • Endometriosis Management: It is effective in managing symptoms of endometriosis by suppressing the growth of endometrial tissue, offering relief to patients suffering from this painful condition.
  • Research in Reproductive Health: Used in studies exploring hormonal regulation and reproductive health, it aids researchers in understanding the mechanisms of hormonal therapies and their effects on various conditions.
  • Clinical Trials: Frequently involved in clinical trials assessing new treatment protocols for weight management and cancer therapies, providing critical data that can lead to improved patient outcomes.

Citations