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Catalog Number:
38005
CAS Number:
13010-47-4
Lomustine
Purity:
≥ 98 % (HPLC)
Synonym(s):
1-(2-chloroéthyl)-3-cyclohexyl-1-nitrosourée
Hazmat
Documents
$64.00 /50 mg
Taille
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Informations sur le produit

Lomustine is a potent alkylating agent widely recognized for its application in oncology, particularly in the treatment of various types of cancer, including brain tumors and Hodgkin's lymphoma. This compound operates by interfering with the DNA replication process, effectively halting the growth of cancer cells. Its unique structure, characterized by the presence of a nitrosourea group, enhances its ability to cross the blood-brain barrier, making it particularly valuable in treating central nervous system malignancies. Researchers and healthcare professionals appreciate Lomustine for its efficacy and the potential to be used in combination therapies, which can improve patient outcomes.

In addition to its primary use in cancer treatment, Lomustine has shown promise in veterinary medicine for treating tumors in animals. Its versatility and effectiveness make it a critical component in both human and veterinary oncology. As a well-established chemotherapeutic agent, Lomustine continues to be a focal point of research, with ongoing studies exploring its potential in novel therapeutic regimens. With its proven track record and significant clinical applications, Lomustine remains an essential compound for professionals in the medical and research fields.

Numéro CAS 
13010-47-4
Formule moléculaire
C9H16ClN3O2
Poids moléculaire 
233.7
Point de fusion 
89 - 93 ?C
Informations générales
Numéro CAS 
13010-47-4
Formule moléculaire
C9H16ClN3O2
Poids moléculaire 
233.7
Point de fusion 
89 - 93 ?C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Lomustine is widely utilized in research focused on

  • Cancer Treatment: Primarily used as a chemotherapy agent for treating various types of cancers, including brain tumors and Hodgkin's lymphoma, offering targeted action against malignant cells.
  • Veterinary Medicine: Employed in veterinary oncology for treating tumors in pets, providing an effective option for animal healthcare professionals.
  • Research Applications: Utilized in laboratory settings to study the mechanisms of cancer cell resistance and the development of new therapeutic strategies, aiding researchers in understanding tumor biology.
  • Combination Therapy: Often used in conjunction with other chemotherapeutic agents to enhance treatment efficacy, allowing for a more comprehensive approach to cancer management.
  • Drug Development: Serves as a model compound in the development of new nitrosourea derivatives, facilitating advancements in cancer pharmacology and improving treatment outcomes.

Citations