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Catalog Number:
37991
CAS Number:
83915-83-7
Lisinopril dihydraté
Purity:
≥ 98 % (dosage par titrage)
Synonym(s):
1-[Na-[( S )-1-carboxy-3-phénylpropyl]-L-lysyl]-L-proline dihydraté
Documents
$94.54 /1G
Taille
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Informations sur le produit

Lisinopril dihydrate is a potent angiotensin-converting enzyme (ACE) inhibitor widely utilized in the management of hypertension and heart failure. This compound is recognized for its ability to lower blood pressure by inhibiting the conversion of angiotensin I to angiotensin II, a peptide that constricts blood vessels. Its efficacy in reducing cardiovascular events makes it a staple in cardiovascular therapy. Lisinopril dihydrate is also employed in the treatment of diabetic nephropathy, showcasing its versatility in managing conditions related to kidney function.

Researchers and healthcare professionals appreciate Lisinopril dihydrate for its favorable pharmacokinetic profile, which allows for once-daily dosing, enhancing patient compliance. Its dihydrate form ensures stability and solubility, making it suitable for various formulations, including tablets and injectables. The compound's unique mechanism of action and its role in improving patient outcomes in chronic conditions underscore its significance in modern medicine.

Numéro CAS 
83915-83-7
Formule moléculaire
C21H31O5N3 · 2H2O
Poids moléculaire 
441.53
Point de fusion 
147 - 149 °C
Rotation optique 
[a] 20 D = -42 à -48 ° (C = 1, 0,25 mol/L de solution tampon d'acétate de zinc) (calculé sur une substance anh.)
Informations générales
Numéro CAS 
83915-83-7
Formule moléculaire
C21H31O5N3 · 2H2O
Poids moléculaire 
441.53
Point de fusion 
147 - 149 °C
Rotation optique 
[a] 20 D = -42 à -48 ° (C = 1, 0,25 mol/L de solution tampon d'acétate de zinc) (calculé sur une substance anh.)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Lisinopril dihydrate is widely utilized in research focused on:

  • Hypertension Treatment: It is primarily used as an antihypertensive medication, helping to lower blood pressure in patients with hypertension, which is crucial for reducing the risk of heart disease and stroke.
  • Heart Failure Management: This compound is effective in treating heart failure, improving survival rates and quality of life for patients by reducing the workload on the heart.
  • Diabetic Kidney Disease: Lisinopril dihydrate is beneficial in protecting kidney function in diabetic patients, making it a vital component in managing diabetic nephropathy.
  • Research in Cardiovascular Health: It is widely studied in clinical trials to understand its effects on cardiovascular health, providing valuable data that can lead to improved treatment protocols.
  • Combination Therapies: This compound is often used in combination with other medications, enhancing therapeutic outcomes for various cardiovascular conditions while minimizing side effects compared to other treatments.

Citations