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Catalog Number:
37970
CAS Number:
220127-57-1
Mésylate d'imatinib
Purity:
≥ 98 % (HPLC)
Synonym(s):
Méthanesulfonate d'imatinib
Documents
$62.59 /100 mg
Taille
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Informations sur le produit

Imatinib mesylate is a potent tyrosine kinase inhibitor primarily used in the treatment of various cancers, including chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). This compound works by selectively inhibiting the BCR-ABL fusion protein, which is responsible for the uncontrolled proliferation of cancer cells. Its unique mechanism of action makes it a cornerstone in targeted cancer therapy, providing significant benefits over traditional chemotherapy by minimizing damage to healthy cells and reducing side effects.

In addition to its primary applications in oncology, Imatinib mesylate has shown promise in treating other conditions such as systemic mastocytosis and certain types of dermatofibrosarcoma. Researchers and healthcare professionals appreciate its effectiveness and specificity, which have led to improved patient outcomes and quality of life. With ongoing studies exploring its potential in combination therapies and new indications, Imatinib mesylate remains a critical compound in the pharmaceutical landscape, offering hope for patients with challenging diagnoses.

Numéro CAS 
220127-57-1
Formule moléculaire
C29H31N7O · CH4O3S
Poids moléculaire 
589.72
Informations générales
Numéro CAS 
220127-57-1
Formule moléculaire
C29H31N7O · CH4O3S
Poids moléculaire 
589.72
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Imatinib mesylate is widely utilized in research focused on:

  • Cancer Treatment: Primarily used in the treatment of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs), providing targeted therapy that significantly improves patient outcomes.
  • Pharmaceutical Development: Serves as a key compound in the development of new cancer therapies, allowing researchers to explore combination treatments that enhance efficacy and reduce resistance.
  • Biomarker Research: Used in studies to identify biomarkers for cancer progression, helping to tailor personalized treatment plans based on individual patient profiles.
  • Drug Resistance Studies: A valuable tool for investigating mechanisms of drug resistance in cancer cells, aiding in the development of next-generation therapies that can overcome these challenges.
  • Clinical Trials: Frequently involved in clinical trials aimed at assessing new formulations or delivery methods, contributing to advancements in cancer care and improving patient quality of life.

Citations