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Catalog Number:
37913
CAS Number:
107007-99-8
Chlorhydrate de granisétron
Purity:
≥ 98 % (dosage par titration, HPLC)
Synonym(s):
Chlorhydrate de 1-méthyl- N -[(3-endo)-9-méthyl-9-azabicyclo[3.3.1]non-3-yl]-1 H -indazole-3-carboxamide
Documents
$70.91 /200 mg
Taille
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Product Information

Granisetron hydrochloride is a potent antiemetic agent widely utilized in the medical field to prevent nausea and vomiting associated with chemotherapy and radiotherapy. This compound acts as a selective serotonin 5-HT3 receptor antagonist, effectively blocking the action of serotonin, which is a key mediator in the vomiting reflex. Its high affinity for the 5-HT3 receptor makes it particularly effective in managing acute and delayed nausea, providing significant relief for patients undergoing cancer treatments.

In addition to its primary use in oncology, Granisetron hydrochloride has also found applications in postoperative care, where it helps mitigate nausea and vomiting following surgery. Its favorable pharmacokinetic profile allows for both oral and intravenous administration, making it versatile for various clinical settings. Researchers and healthcare professionals appreciate Granisetron hydrochloride for its efficacy and safety profile, which often leads to improved patient compliance and quality of life during challenging treatment regimens.

Synonyms
Chlorhydrate de 1-méthyl- N -[(3-endo)-9-méthyl-9-azabicyclo[3.3.1]non-3-yl]-1 H -indazole-3-carboxamide
CAS Number
107007-99-8
Purity
≥ 98 % (dosage par titration, HPLC)
Molecular Formula
C18H24N4O · HCl
Molecular Weight
348.88
MDL Number
MFCD01747034
PubChem ID
65264
Melting Point
292 °C (déc.)
Appearance
Poudre blanche à presque blanche à cristal
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Chlorhydrate de 1-méthyl- N -[(3-endo)-9-méthyl-9-azabicyclo[3.3.1]non-3-yl]-1 H -indazole-3-carboxamide
CAS Number
107007-99-8
Purity
≥ 98 % (dosage par titration, HPLC)
Molecular Formula
C18H24N4O · HCl
Molecular Weight
348.88
MDL Number
MFCD01747034
PubChem ID
65264
Melting Point
292 °C (déc.)
Appearance
Poudre blanche à presque blanche à cristal
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Granisetron hydrochloride is widely utilized in research focused on:

  • Anti-Nausea Treatments: It is primarily used in oncology to prevent nausea and vomiting caused by chemotherapy, providing relief for patients undergoing cancer treatment.
  • Postoperative Care: This compound is effective in managing postoperative nausea and vomiting, improving recovery experiences for patients after surgery.
  • Clinical Trials: Researchers often use it in clinical studies to evaluate its effectiveness and safety in various patient populations, contributing to advancements in medical protocols.
  • Formulation Development: Granisetron hydrochloride is employed in the development of oral and injectable formulations, allowing for flexible administration routes tailored to patient needs.
  • Comparative Studies: It serves as a benchmark in studies comparing new antiemetic drugs, helping to establish efficacy and safety profiles against existing treatments.