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Catalog Number:
37883
CAS Number:
72509-76-3
Félodipine
Grade:
USP
Purity:
98 - 101 % (dosage, sur une base sèche)
Synonym(s):
Acide 4-(2,3-dichlorophényl)-1,4-dihydro-2,6-diméthyl-3,5-pyridinedicarboxylique Ester éthylique et méthylique, 4-(2,3-dichlorophényl)-1,4-dihydro-2,6-diméthyl-3,5-pyridinedicarboxylate d'éthyle et de méthyle
Hazmat
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Product Information

Felodipine is a potent calcium channel blocker primarily used in the management of hypertension and angina. This dihydropyridine derivative works by inhibiting calcium influx into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Its unique structure, featuring a dichlorophenyl group, enhances its selectivity and efficacy, making it a preferred choice in clinical settings. Felodipine is often formulated in extended-release preparations, allowing for once-daily dosing, which improves patient compliance and therapeutic outcomes.

In addition to its cardiovascular applications, Felodipine is also being explored for its potential benefits in treating other conditions, such as Raynaud's phenomenon and certain types of heart failure. Researchers appreciate its favorable pharmacokinetic profile, which includes a long half-life and minimal side effects compared to other antihypertensives. This compound's ability to provide sustained blood pressure control while minimizing adverse reactions positions it as a valuable option for healthcare professionals seeking effective treatment strategies.

Synonyms
Acide 4-(2,3-dichlorophényl)-1,4-dihydro-2,6-diméthyl-3,5-pyridinedicarboxylique Ester éthylique et méthylique, 4-(2,3-dichlorophényl)-1,4-dihydro-2,6-diméthyl-3,5-pyridinedicarboxylate d'éthyle et de méthyle
CAS Number
72509-76-3
Purity
98 - 101 % (dosage, sur une base sèche)
Grade
USP
Molecular Formula
C 18 H 19 Cl 2 NO 4
Molecular Weight
384.25
MDL Number
MFCD00868316
PubChem ID
3333
Melting Point
142 - 146 °C
Appearance
Poudre cristalline blanche à jaune pâle
Conditions
Magasin chez RT
General Information
Synonyms
Acide 4-(2,3-dichlorophényl)-1,4-dihydro-2,6-diméthyl-3,5-pyridinedicarboxylique Ester éthylique et méthylique, 4-(2,3-dichlorophényl)-1,4-dihydro-2,6-diméthyl-3,5-pyridinedicarboxylate d'éthyle et de méthyle
CAS Number
72509-76-3
Purity
98 - 101 % (dosage, sur une base sèche)
Grade
USP
Molecular Formula
C 18 H 19 Cl 2 NO 4
Molecular Weight
384.25
MDL Number
MFCD00868316
PubChem ID
3333
Melting Point
142 - 146 °C
Appearance
Poudre cristalline blanche à jaune pâle
Conditions
Magasin chez RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Oui
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Felodipine is widely utilized in research focused on:

  • Cardiovascular Health: Primarily used as an antihypertensive agent, it helps manage high blood pressure, reducing the risk of heart-related complications.
  • Pharmaceutical Development: Employed in the formulation of various medications, it serves as a model compound for studying drug absorption and metabolism.
  • Clinical Trials: Frequently involved in clinical studies aimed at evaluating the efficacy of new treatments for hypertension and related cardiovascular conditions.
  • Research on Drug Interactions: Useful in studies assessing how different substances interact with antihypertensive medications, aiding in safer prescribing practices.
  • Patient Compliance Studies: Investigated for its role in improving patient adherence to treatment regimens due to its extended-release formulations, which require less frequent dosing.

Citations