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Catalog Number:
37863
CAS Number:
84680-54-6
Énalaprilate dihydraté
Purity:
≥ 98 % (HPLC)
Synonym(s):
N -[(1S)-1-carboxy-3-phénylpropyl]-L-alanyl-L-prolinedihydraté, Acide énalaprilique dihydraté
Documents
$148.22 /50 mg
Taille
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Informations sur le produit

Enalaprilat dihydrate is a potent angiotensin-converting enzyme (ACE) inhibitor widely utilized in the management of hypertension and heart failure. This compound is recognized for its ability to effectively lower blood pressure by inhibiting the conversion of angiotensin I to angiotensin II, a powerful vasoconstrictor. Its unique dihydrate form enhances solubility and bioavailability, making it an ideal choice for pharmaceutical formulations. Enalaprilat dihydrate is particularly valuable in clinical settings, where it is often administered intravenously for rapid control of blood pressure in hypertensive emergencies.

In addition to its cardiovascular applications, Enalaprilat dihydrate is also being explored for its potential benefits in renal protection and diabetic nephropathy management. Researchers appreciate its dual action of not only lowering blood pressure but also providing renal benefits, making it a versatile compound in therapeutic regimens. Its efficacy and safety profile have made it a staple in both acute and chronic treatment protocols, ensuring that patients receive optimal care.

Numéro CAS 
84680-54-6
Formule moléculaire
C18H24N2O5 · 2H2O
Poids moléculaire 
384.43
Rotation optique 
[a] 20 D = -50 à -54 ° (C=1 dans MeOH (calculé sur une substance anh.))
Informations générales
Numéro CAS 
84680-54-6
Formule moléculaire
C18H24N2O5 · 2H2O
Poids moléculaire 
384.43
Rotation optique 
[a] 20 D = -50 à -54 ° (C=1 dans MeOH (calculé sur une substance anh.))
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
-
Réglementé par la DEA
Non
Avertissements 
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Applications

Enalaprilat dihydrate is widely utilized in research focused on:

  • Hypertension Treatment: This compound is primarily used in the treatment of high blood pressure, providing a reliable option for patients who require effective antihypertensive therapy.
  • Heart Failure Management: It is beneficial in managing heart failure, helping to improve heart function and reduce the risk of hospitalization for patients with this condition.
  • Pharmaceutical Research: Enalaprilat dihydrate serves as a crucial reference compound in drug development studies, particularly in the exploration of ACE inhibitors and their effects on cardiovascular health.
  • Clinical Trials: It is frequently used in clinical trials to evaluate the efficacy and safety of new medications aimed at treating cardiovascular diseases, providing a benchmark for comparison.
  • Educational Purposes: In academic settings, it is used in pharmacology and medicinal chemistry courses to illustrate the mechanisms of action of ACE inhibitors and their therapeutic applications.

Citations