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Catalog Number:
37791
CAS Number:
33286-22-5
Chlorhydrate de (+)-cis-diltiazem
Purity:
98 - 102 % (dosage)
Synonym(s):
(2S,3S)-(+)-3-acétoxy-2,3-dihydro-5-[2-(diméthylamino)éthyl]-2-(4-méthoxyphényl)-1,5-benzothiazépin-4(5 H )-onehydrochlorure
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Taille
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Informations sur le produit

(+)-cis-Diltiazem hydrochloride is a potent calcium channel blocker widely utilized in the treatment of cardiovascular conditions such as hypertension and angina. This compound functions by inhibiting calcium influx into cardiac and smooth muscle cells, leading to vasodilation and reduced heart workload. Its unique structure allows for effective modulation of heart rate and blood pressure, making it a valuable asset in clinical settings. Researchers and healthcare professionals appreciate its dual action on both the heart and blood vessels, which enhances its therapeutic profile compared to other calcium channel blockers.

In addition to its medical applications, (+)-cis-Diltiazem hydrochloride is also explored in pharmaceutical research for developing novel formulations and drug delivery systems. Its favorable pharmacokinetic properties and compatibility with various excipients make it an ideal candidate for innovative therapeutic strategies. This compound's versatility and effectiveness in managing cardiovascular diseases underscore its significance in both clinical and research environments, providing a reliable option for healthcare professionals seeking effective treatment solutions.

Numéro CAS 
33286-22-5
Formule moléculaire
C22H26N2O4S · HCl
Poids moléculaire 
450.98
Point de fusion 
210 - 215 °C
Rotation optique 
[a] D 20 = 110 - 116 ° (C = 1 dans l'eau)
Informations générales
Numéro CAS 
33286-22-5
Formule moléculaire
C22H26N2O4S · HCl
Poids moléculaire 
450.98
Point de fusion 
210 - 215 °C
Rotation optique 
[a] D 20 = 110 - 116 ° (C = 1 dans l'eau)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

(+)-cis-Diltiazem hydrochloride is widely utilized in research focused on

  • Cardiovascular Health: This compound is primarily used in the treatment of hypertension and angina. It helps relax blood vessels, improving blood flow and reducing heart workload, making it essential in cardiology.
  • Pharmaceutical Development: Researchers often use it as a reference compound in drug formulation studies due to its established efficacy and safety profile, aiding in the development of new cardiovascular medications.
  • Clinical Trials: It serves as a standard in clinical trials assessing new treatments for heart diseases, providing a benchmark for efficacy and safety comparisons.
  • Research on Drug Interactions: The compound is studied for its interactions with other medications, helping to understand polypharmacy effects, particularly in elderly patients with multiple health issues.
  • Educational Purposes: It is frequently used in pharmacology courses to teach students about calcium channel blockers, their mechanisms of action, and their therapeutic applications.

Citations