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Catalog Number:
37738
CAS Number:
305-03-3
Chlorambucil
Purity:
≥ 98 % (dosage par titration, GC)
Synonym(s):
Acide 4-[4-[bis(2-chloroéthyl)amino]phényl]butyrique
Hazmat
Documents
$90.34 /200 mg
Taille
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Informations sur le produit

Chlorambucil is a potent alkylating agent primarily used in the treatment of certain types of cancer, particularly chronic lymphocytic leukemia (CLL) and lymphoma. This compound functions by interfering with the DNA replication process, making it effective in targeting rapidly dividing cancer cells. Its ability to penetrate cell membranes allows for effective delivery within the body, enhancing its therapeutic efficacy. Chlorambucil is also recognized for its relatively mild side effect profile compared to other chemotherapeutic agents, making it a preferred choice in long-term cancer management.

In addition to its primary use in oncology, Chlorambucil has applications in research settings, particularly in studies focused on cancer biology and drug resistance mechanisms. Its unique properties allow researchers to explore the effects of DNA damage and repair pathways, contributing to the development of novel therapeutic strategies. With its established role in cancer treatment and ongoing research applications, Chlorambucil remains a valuable compound in both clinical and laboratory environments.

Numéro CAS 
305-03-3
Formule moléculaire
C14H19Cl2NO2
Poids moléculaire 
304.21
Point de fusion 
65 - 69 ?C
Informations générales
Numéro CAS 
305-03-3
Formule moléculaire
C14H19Cl2NO2
Poids moléculaire 
304.21
Point de fusion 
65 - 69 ?C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Chlorambucil is widely utilized in research focused on:

  • Cancer Treatment: Primarily used in oncology, it serves as a chemotherapy agent for treating chronic lymphocytic leukemia (CLL) and Hodgkin's lymphoma, helping to slow down cancer cell growth.
  • Immunosuppressive Therapy: Employed in organ transplantation and autoimmune diseases, it helps suppress the immune response, reducing the risk of organ rejection and managing conditions like rheumatoid arthritis.
  • Pharmaceutical Research: Used in drug development studies, chlorambucil aids researchers in understanding the mechanisms of action of alkylating agents and their effects on DNA, providing insights for creating new therapies.
  • Veterinary Medicine: It is also applied in veterinary oncology for treating certain types of cancers in animals, offering a therapeutic option where traditional treatments may be less effective.
  • Combination Therapies: Often used in combination with other chemotherapeutic agents, chlorambucil enhances treatment efficacy, allowing for lower doses of each drug and potentially reducing side effects.

Citations