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Catalog Number:
37119
CAS Number:
18303-04-3
N-(tert-Butoxycarbonyl)-p-toluènesulfonamide
Purity:
≥ 98 % (dosage par titration)
Synonym(s):
N-Boc-p-toluènesulfonamide
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Product Information

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide is a versatile compound widely utilized in organic synthesis and pharmaceutical research. This compound, also known as tert-butyl N-(4-methylphenyl)sulfonylcarbamate, serves as a protective group for amines in various chemical reactions, enhancing the efficiency of synthetic pathways. Its unique structure allows for selective reactions, making it an invaluable tool in the development of complex molecules, particularly in the synthesis of pharmaceuticals and agrochemicals. Researchers appreciate its stability under a range of conditions, which facilitates its use in multi-step synthesis processes.

In addition to its role in organic synthesis, N-(tert-Butoxycarbonyl)-p-toluenesulfonamide is also employed in the preparation of sulfonamide derivatives, which are crucial in medicinal chemistry for developing antibacterial agents. Its ability to provide a stable and easily removable protecting group makes it a preferred choice among chemists looking to streamline their synthetic routes. With its practical applications and benefits, this compound is essential for researchers aiming to innovate in drug discovery and development.

Synonyms
N-Boc-p-toluènesulfonamide
CAS Number
18303-04-3
Purity
≥ 98 % (dosage par titration)
Molecular Formula
C 12 H 17 NON 4 S
Molecular Weight
271.33
MDL Number
MFCD00134267
PubChem ID
688170
Melting Point
121 - 123 ?C
Appearance
Poudre ou cristaux blancs
Conditions
Magasin chez RT
General Information
Synonyms
N-Boc-p-toluènesulfonamide
CAS Number
18303-04-3
Purity
≥ 98 % (dosage par titration)
Molecular Formula
C 12 H 17 NON 4 S
Molecular Weight
271.33
MDL Number
MFCD00134267
PubChem ID
688170
Melting Point
121 - 123 ?C
Appearance
Poudre ou cristaux blancs
Conditions
Magasin chez RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a protecting group in the synthesis of various pharmaceuticals, allowing for selective reactions without interfering with other functional groups.
  • Organic Synthesis: It is commonly used in organic chemistry as a reagent for the preparation of sulfonamide derivatives, which are important in creating biologically active compounds.
  • Research in Medicinal Chemistry: Researchers leverage its properties to develop new drugs, particularly in the field of antibiotics and cancer treatments, due to its ability to enhance solubility and stability.
  • Bioconjugation: The compound is employed in bioconjugation techniques, linking biomolecules with therapeutic agents, which is crucial in targeted drug delivery systems.
  • Analytical Chemistry: It is used as a standard in analytical methods to quantify sulfonamide compounds, aiding in quality control and regulatory compliance in pharmaceutical manufacturing.

Citations