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Catalog Number:
33640
CAS Number:
1198791-58-0
Fmoc-α-méthyl-L-propargylglycine
Synonym(s):
Fmoc-α-Me-L-Pra-OH, Acide Fmoc-( S -2-amino-2-méthyl-4-pentynoïque
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$100.05 /25 mg
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Product Information

Fmoc-a-methyl-L-propargylglycine is a versatile amino acid derivative that serves as a crucial building block in peptide synthesis and drug development. This compound is particularly valued for its unique propargyl group, which facilitates the introduction of various functional groups through click chemistry, making it an essential tool for researchers in medicinal chemistry and bioconjugation. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while maintaining stability during synthesis.

In practical applications, Fmoc-a-methyl-L-propargylglycine has been utilized in the development of peptide-based therapeutics, including those targeting cancer and neurological disorders. Its ability to enhance the bioactivity of peptides while providing a handle for further modifications makes it a preferred choice among chemists. Additionally, the compound's compatibility with solid-phase peptide synthesis techniques ensures efficient and high-yield production of complex peptides, catering to the needs of both academic and industrial researchers.

Synonyms
Fmoc-α-Me-L-Pra-OH, Acide Fmoc-( S -2-amino-2-méthyl-4-pentynoïque
CAS Number
1198791-58-0
Molecular Formula
C 21 H 194
Molecular Weight
349.38
MDL Number
MFCD14636468
PubChem ID
53398624
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Fmoc-α-Me-L-Pra-OH, Acide Fmoc-( S -2-amino-2-méthyl-4-pentynoïque
CAS Number
1198791-58-0
Molecular Formula
C 21 H 194
Molecular Weight
349.38
MDL Number
MFCD14636468
PubChem ID
53398624
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-a-methyl-L-propargylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of unique functionalities into peptide chains.
  • Drug Development: Its structure enables the exploration of new drug candidates, especially in the development of inhibitors for various biological targets, enhancing the potential for therapeutic applications.
  • Bioconjugation: The alkyne group in the compound facilitates click chemistry, making it valuable for bioconjugation techniques, which are essential in creating targeted drug delivery systems and imaging agents.
  • Research in Neuroscience: It is used in studies related to neurotransmitter systems, where modifications of peptides can lead to insights into neurological functions and disorders.
  • Material Science: The compound's unique properties allow it to be incorporated into polymer systems, leading to the development of advanced materials with specific functionalities, such as improved mechanical strength or biocompatibility.

Citations