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Catalog Number:
33630
Fmoc-α-méthyl-L-3-fluorophénylalanine
Purity:
≥ 99,5 % (HPLC chirale, HPLC)
Synonym(s):
Fmoc-α-Me-L-Phe(3-F)-OH, Acide Fmoc-( S )-2-amino-2-méthyl-3-(3-fluorophényl)propanoïque
Documents
$60.00 /100 mg
Taille
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Product Information

Fmoc-a-methyl-L-3-fluorophenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorinated aromatic side chain, which enhances its biochemical properties, making it an excellent choice for researchers focusing on the design of novel therapeutics. Its unique structure allows for increased stability and specificity in peptide interactions, which is crucial in the development of targeted drug delivery systems.

In addition to its applications in medicinal chemistry, Fmoc-a-methyl-L-3-fluorophenylalanine is also employed in the synthesis of complex peptides and proteins, facilitating the study of protein folding and function. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group provides ease of handling during synthesis, allowing for efficient deprotection and subsequent reactions. This compound stands out for its ability to introduce fluorine into peptide sequences, which can enhance the pharmacokinetic properties of the resulting peptides, making it a preferred choice for researchers and industry professionals alike.

Synonyms
Fmoc-α-Me-L-Phe(3-F)-OH, Acide Fmoc-( S )-2-amino-2-méthyl-3-(3-fluorophényl)propanoïque
Purity
≥ 99,5 % (HPLC chirale, HPLC)
Molecular Formula
C 25 H 22 FNO 4
Molecular Weight
419.45
MDL Number
MFCD22887379
Appearance
Poudre blanche
Optical Rotation
[a] 20 D = -35 ± 1 ° (C = 1 dans DMF)
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Fmoc-α-Me-L-Phe(3-F)-OH, Acide Fmoc-( S )-2-amino-2-méthyl-3-(3-fluorophényl)propanoïque
Purity
≥ 99,5 % (HPLC chirale, HPLC)
Molecular Formula
C 25 H 22 FNO 4
Molecular Weight
419.45
MDL Number
MFCD22887379
Appearance
Poudre blanche
Optical Rotation
[a] 20 D = -35 ± 1 ° (C = 1 dans DMF)
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-a-methyl-L-3-fluorophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of unique amino acid side chains that can enhance peptide stability and functionality.
  • Drug Development: Its fluorinated structure can improve the pharmacokinetic properties of peptide-based drugs, making it valuable in the pharmaceutical industry for developing more effective therapeutic agents.
  • Bioconjugation: The compound can be used in bioconjugation techniques, where it helps in attaching peptides to other biomolecules, facilitating the creation of targeted drug delivery systems.
  • Research in Neuroscience: Due to its structural properties, it is utilized in studies related to neuropeptides, aiding researchers in understanding neurological functions and developing treatments for related disorders.
  • Analytical Chemistry: This compound can be employed in analytical methods such as mass spectrometry, providing insights into peptide structure and behavior, which is crucial for both academic and industrial research.

Citations