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Catalog Number:
33629
Fmoc-α-méthyl-D-3-fluorophénylalanine
Purity:
≥ 98% (Chiral HPLC)
Synonym(s):
Fmoc-α-Me-D-Phe(3-F)-OH, Acide Fmoc-( R -2-amino-2-méthyl-3-(3-fluorophényl)propanoïque
Documents
$60.00 /100 mg
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Product Information

Fmoc-a-methyl-D-3-fluorophenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorinated aromatic side chain, which enhances its biochemical properties, making it an ideal candidate for the design of novel therapeutics. Its unique structure allows for increased stability and selectivity in biological applications, particularly in the development of peptide-based drugs. Researchers appreciate its role in facilitating the synthesis of peptides with enhanced pharmacological profiles, leading to improved efficacy and reduced side effects.

In addition to its applications in medicinal chemistry, Fmoc-a-methyl-D-3-fluorophenylalanine is also employed in the study of protein interactions and enzyme mechanisms. The incorporation of fluorine into peptide sequences can provide insights into molecular recognition processes and improve the understanding of biological systems. This compound stands out for its ability to enhance the properties of peptides while maintaining compatibility with standard coupling techniques, making it a preferred choice for researchers aiming to innovate in the fields of biochemistry and pharmaceutical development.

Synonyms
Fmoc-α-Me-D-Phe(3-F)-OH, Acide Fmoc-( R -2-amino-2-méthyl-3-(3-fluorophényl)propanoïque
Purity
≥ 98% (Chiral HPLC)
Molecular Formula
C 25 H 22 FNO 4
Molecular Weight
419.45
MDL Number
MFCD22887398
Appearance
White powder
Optical Rotation
[a]D25 = +23 ±2 °(C=1 in DMF)
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Fmoc-α-Me-D-Phe(3-F)-OH, Acide Fmoc-( R -2-amino-2-méthyl-3-(3-fluorophényl)propanoïque
Purity
≥ 98% (Chiral HPLC)
Molecular Formula
C 25 H 22 FNO 4
Molecular Weight
419.45
MDL Number
MFCD22887398
Appearance
White powder
Optical Rotation
[a]D25 = +23 ±2 °(C=1 in DMF)
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-a-methyl-D-3-fluorophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create custom sequences for various applications in drug development and biological studies.
  • Drug Discovery: Its unique fluorinated structure enhances the pharmacokinetic properties of peptides, making it valuable in the design of novel therapeutics that require improved stability and bioavailability.
  • Bioconjugation: The chemical can be used in bioconjugation techniques, facilitating the attachment of peptides to other molecules, such as antibodies or nanoparticles, for targeted drug delivery systems.
  • Research in Neuroscience: Due to its ability to mimic natural amino acids, it is employed in studies related to neurotransmitter function and receptor interactions, contributing to advancements in understanding neurological disorders.
  • Protein Engineering: This compound aids in the modification of proteins, allowing scientists to enhance their properties or create novel functionalities, which is essential for various applications in biotechnology and pharmaceuticals.

Citations